Foot-and-mouth disease virus serotypes detected in Tanzania from 2003 to 2010: Conjectured status and future prospects

Onderstepoort Journal of Veterinary Research

 
 
Field Value
 
Title Foot-and-mouth disease virus serotypes detected in Tanzania from 2003 to 2010: Conjectured status and future prospects
 
Creator Kasanga, Christopher J. Sallu, Raphael Kivaria, Fredrick Mkama, Mathias Masambu, Joseph Yongolo, Mmeta Das, Sachindra Mpelumbe-Ngeleja, Chanasa Wambura, Philemon N. King, Donald P. Rweyemamu, Mark M.
 
Subject — Foot-and-mouth disease; FMDV serotypes; Antigen ELISA; spatiotemporal distribution; Tanzania
Description This study was conducted to investigate the presence of foot-and-mouth disease virus (FMDV) in different geographic locations of Tanzania. Epithelial tissues and fluids (n = 364) were collected from cattle exhibiting oral and foot vesicular lesions suggestive of FMD and submitted for routine FMD diagnosis. The analysis of these samples collected during the period of 2002 and 2010 was performed by serotype-specific antigen capture ELISA to determine the presence of FMDV. The results of this study indicated that 167 out of 364 (46.1%) of the samples contained FMDV antigen. Of the 167 positive samples, 37 (28.4%) were type O, 7 (4.1%) type A, 45 (21.9%) SAT 1 and 79 (45.6%) SAT 2. Two FMDV serotypes (O and SAT 2) were widely distributed throughout Tanzania whilst SAT 1 and A types were only found in the Eastern zone. Our findings suggest that serotypes A, O, SAT 1 and SAT 2 prevail in Tanzania and are associated with the recent FMD outbreaks. The lack of comprehensive animal movement records and inconsistent vaccination programmes make it difficult to determine the exact source of FMD outbreaks or to trace the transmission of the disease over time. Therefore, further collection and analysis of samples from domestic and wild animals are being undertaken to investigate the genetic and antigenic characteristics of the circulating strains, so that a rational method to control FMD in Tanzania and the neighbouring countries can be recommended.
 
Publisher AOSIS
 
Contributor
Date 2012-06-20
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ojvr.v79i2.462
 
Source Onderstepoort Journal of Veterinary Research; Vol 79, No 2 (2012); 4 pages 2219-0635 0030-2465
 
Language eng
 
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https://ojvr.org/index.php/ojvr/article/view/462/615 https://ojvr.org/index.php/ojvr/article/view/462/647 https://ojvr.org/index.php/ojvr/article/view/462/702 https://ojvr.org/index.php/ojvr/article/view/462/530 https://ojvr.org/index.php/ojvr/article/downloadSuppFile/462/482 https://ojvr.org/index.php/ojvr/article/downloadSuppFile/462/483
 
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Rights Copyright (c) 2012 Christopher J. Kasanga, Raphael Sallu, Fredrick Kivaria, Mathias Mkama, Joseph Masambu, Mmeta Yongolo, Sachindra Das, Chanasa Mpelumbe-Ngeleja, Philemon N. Wambura, Donald P. King, Mark M. Rweyemamu https://creativecommons.org/licenses/by-nd/4.0
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