Rift Valley fever virus in small ruminants in the Democratic Republic of the Congo

Onderstepoort Journal of Veterinary Research

Field Value
Title Rift Valley fever virus in small ruminants in the Democratic Republic of the Congo
Creator Tshilenge, Georges M. Mulumba, Mfumu L.K Misinzo, Gerald Noad, Rob Dundon, William G.
Subject Infectious diseases Rift Valley fever; ruminants; serology; Democratic Republic of the Congo; prevalence
Description Rift Valley fever (RVF) is a zoonotic viral disease caused by the RVF phlebovirus (RVFV) that infects a variety of animal species including sheep and goats. Sera (n = 893) collected between 2013 and 2015 from randomly selected indigenous sheep and goats in seven provinces of the Democratic Republic of the Congo (DRC) were tested for the presence of specific immunoglobulin G (IgG) and M (IgM) against RVFV, using two commercially available enzyme-linked immunosorbent assays. The reverse transcription polymerase chain reaction (RT-PCR) was also used to detect RVFV nucleic acid. There was significant variation in true seroprevalence of RVFV for both sheep and goats between the seven provinces investigated. Values ranged from 0.0 (95% confidence interval [CI] 0.0–6.55) to 23.81 (95% CI 12.03–41.76) for goat and 0.0 (95% CI 0.0–7.56) to 37.11 (95% CI 15.48–65.94) for sheep, respectively. One serum (1.85%) out of 54 that tested positive for IgG was found to be IgM-positive. This same sample was also positive by RT-PCR indicating an active or recent infection. These findings report the presence of RVFV in small ruminants in the DRC for the first time and indicate variations in exposure to the virus in different parts of the country.
Publisher AOSIS
Contributor Wellcome Trust
Date 2019-10-10
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ojvr.v86i1.1737
Source Onderstepoort Journal of Veterinary Research; Vol 86, No 1 (2019); 5 pages 2219-0635 0030-2465
Language eng
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https://ojvr.org/index.php/ojvr/article/view/1737/2006 https://ojvr.org/index.php/ojvr/article/view/1737/2005 https://ojvr.org/index.php/ojvr/article/view/1737/2007 https://ojvr.org/index.php/ojvr/article/view/1737/1995
Coverage Democratic Repubilc of the Congo — —
Rights Copyright (c) 2019 Georges M. Tshilenge, Mfumu L.K Mulumba, Gerald Misinzo, Rob Noad, William G. Dundon https://creativecommons.org/licenses/by/4.0