Studies towards optimising the isolation of diplonine, a neurotoxin isolated from cultures of Stenocarpella maydis (Berk.) Sacc.
Onderstepoort Journal of Veterinary Research
| Field | Value | |
| Title | Studies towards optimising the isolation of diplonine, a neurotoxin isolated from cultures of Stenocarpella maydis (Berk.) Sacc. | |
| Creator | Snyman, Leendert D. Flett, Bradley C. Schultz, Rowina A. | |
| Description | Diplonine, a mycotoxin that induces neurotoxic clinical signs in the guinea pig, resembling those occurring in cattle and sheep with diplodiosis, was isolated previously from a Stenocarpella maydisculture. Knowledge of the chemical properties of the toxin, which was characterised as a substituted ß-cyclopropylamino acid, enabled amendments in the present study to the initial steps of the isolation procedure. Extraction with water and fractionation by cation exchange chromatography improved the efficiency of isolation, potentially allowing the preparation of larger amounts of the toxin. | |
| Publisher | AOSIS | |
| Date | 2014-11-12 | |
| Identifier | 10.4102/ojvr.v81i1.765 | |
| Source | Onderstepoort Journal of Veterinary Research; Vol 81, No 1 (2014); 4 pages 2219-0635 0030-2465 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ojvr.org/index.php/ojvr/article/view/765/1157
https://ojvr.org/index.php/ojvr/article/view/765/1158
https://ojvr.org/index.php/ojvr/article/view/765/1159
https://ojvr.org/index.php/ojvr/article/view/765/1137
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