A systematic review of healthcare-associated infections in Africa: An antimicrobial resistance perspective
African Journal of Laboratory Medicine
| Field | Value | |
| Title | A systematic review of healthcare-associated infections in Africa: An antimicrobial resistance perspective | |
| Creator | Irek, Emmanuel O. Amupitan, Adewale A. Obadare, Temitope O. Aboderin, Aaron O. | |
| Description | Background: Healthcare-associated infection (HCAI) is a global health challenge, not only as an issue of patient safety but also as a major driver of antimicrobial resistance (AMR). It is a major cause of morbidity and mortality with economic consequences.Objective: This review provides an update on the occurrence of HCAI, as well as the contribution of emerging AMR on healthcare delivery in Africa.Methods: We searched PubMed, Cochrane database, African Journals Online and Google Scholar for relevant articles on HCAI in Africa between 2010 and 2017. Preferred reporting items of systematic reviews and meta-analyses guidelines were followed for selection. Thirty-five eligible articles were considered for the qualitative synthesis.Results: Of the 35 eligible articles, more than half (n = 21, 60%) were from East Africa. Klebsiella spp., Staphylococcus aureus, Escherichia coli and Pseudomonas spp. were the common pathogens reported in bloodstream infection, (catheter-associated) urinary tract infection, surgical site infection and healthcare-associated pneumonia. Among these various subtypes of HCAI, methicillin-resistant S. aureus (3.9% – 56.8%) and extended-spectrum beta-lactamase producing Gram-negative bacilli (1.9% – 53.0%) were the most reported antimicrobial resistant pathogens.Conclusion: This review shows a paucity of HCAI surveillance in Africa and an emergence of AMR priority pathogens. Hence, there is a need for a coordinated national and regional surveillance of both HCAI and AMR in Africa. | |
| Publisher | AOSIS | |
| Date | 2018-12-06 | |
| Identifier | 10.4102/ajlm.v7i2.796 | |
| Source | African Journal of Laboratory Medicine; Vol 7, No 2 (2018); 9 pages 2225-2010 2225-2002 | |
| Language | eng | |
| Relation |
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https://ajlmonline.org/index.php/ajlm/article/view/796/1220
https://ajlmonline.org/index.php/ajlm/article/view/796/1219
https://ajlmonline.org/index.php/ajlm/article/view/796/1221
https://ajlmonline.org/index.php/ajlm/article/view/796/1148
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