Cylindrocarpon lichenicola keratomycosis in Nigeria: the challenge of limited access to effective antimicrobials
African Journal of Laboratory Medicine
| Field | Value | |
| Title | Cylindrocarpon lichenicola keratomycosis in Nigeria: the challenge of limited access to effective antimicrobials | |
| Creator | Irek, Emmanuel O. Obadare, Temitope O. Udonwa, Patrick A. Laoye, Olajumoke Abiri, Oyekola V. Adeoye, Adenike O. Aboderin, Aaron O. | |
| Description | Introduction: We report a rare cause of keratitis, due to Cylindrocarpon lichenicola, in a farmer with keratomycosis. Despite the acknowledged virulence of this fungus, a suitable antifungal for its management was not accessible.Case presentation: A 67-year-old farmer presented with a two-week history of pain, mucopurulent discharge, redness and a corneal ulcer with a visual acuity of hand movement in the right eye. With a working diagnosis of infective keratitis, corneal scrapings were taken under a slit lamp biomicroscope for microbiological testing. Direct lactophenol cotton blue mounts revealed septate fungal hyphae, while fungal culture on Sabouraud dextrose agar at room temperature grew woolly mould phenotypically consistent with C. lichenicola.Management and outcome: The patient was started on hourly topical natamycin (5%), ciprofloxacin (0.3%), two-hourly instillation of tobramycin (0.3%) and atropine (1%) twice daily for three months following the isolation of the fungus. The eye healed with a corneal scar and no improvements in visual acuity.Discussion: This infection was difficult to manage due to the inaccessibility of a suitable antifungal, namely, voriconazole in our setting. Hence, there is a need for prompt identification and early institution of suitable antifungals in any patient with suspected keratomycosis. | |
| Publisher | AOSIS | |
| Date | 2017-07-11 | |
| Identifier | 10.4102/ajlm.v6i1.612 | |
| Source | African Journal of Laboratory Medicine; Vol 6, No 1 (2017); 3 pages 2225-2010 2225-2002 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ajlmonline.org/index.php/ajlm/article/view/612/870
https://ajlmonline.org/index.php/ajlm/article/view/612/869
https://ajlmonline.org/index.php/ajlm/article/view/612/871
https://ajlmonline.org/index.php/ajlm/article/view/612/866
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