Primary ciliary dyskinesia in a Staffordshire bull terrier : clinical communication
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Primary ciliary dyskinesia in a Staffordshire bull terrier : clinical communication | |
| Creator | De Scally, M. Lobetti, R.G. Van Wilpe, E. | |
| Description | Primary ciliary dyskinesia (PCD) is a diverse group of inherited structural and functional abnormalities of the respiratory and other cilia, which results in recurrent respiratory tract infections. Primary ciliary dyskinesia was diagnosed in a 14-week old Staffordshire bull terrier that had a history of respiratory disease from 7 weeks of age. Pneumonia was diagnosed on thoracic radiographs and transtracheal aspirate. Transmission electron microscopy of the bronchi and trachea indicated the presence of both primary and secondary ciliary dyskinesia. The most prominent primary defects consisted of absent inner dyneim arms, absent radial spokes and absence of the central microtubules. These defects accounted for 62 % of the total number of cross-sections screened. Non-specific ciliary abnormalities encountered most often were compound cilia, swollen cilia, addition / deletion of peripheral doublets and disorganised axonemes (26 %). To the authors' knowledge, this is the first case of PCD described in the Staffordshire bull terrier and the first report of PCD in South Africa. | |
| Publisher | AOSIS | |
| Date | 2004-06-20 | |
| Identifier | 10.4102/jsava.v75i3.471 | |
| Source | Journal of the South African Veterinary Association; Vol 75, No 3 (2004); 150-152 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/471/455
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