Determinants of active pulmonary tuberculosis in Ambo Hospital, West Ethiopia

African Journal of Primary Health Care & Family Medicine

 
 
Field Value
 
Title Determinants of active pulmonary tuberculosis in Ambo Hospital, West Ethiopia Les déterminants de tuberculose pulmonaire active à l’hôpital d’Ambo, en Ethiopie occidentale
 
Creator Ephrem, Tenna Mengiste, Bezatu Mesfin, Frehiwot Godana, Wanzahun
 
Subject — — — —
Description Objectives: The aim of this study was to determine factors associated with active pulmonary tuberculosis seen in cases in Ambo Hospital, Ethiopia.Design: A facility-based prospective case-control study.Setting: Patients attending Ambo Hospital from 01 December 2011 to 29 March 2012.Participants: The sample included 312 adult patients attending Ambo Hospital. The main outcome measure was presence of active pulmonary tuberculosis (TB).Explanatory measures: Age, gender, occupation, educational status, marital status, place of residence, patient history of TB, family history of TB, human immunodeficiency virus (HIV) infection, smoking, alcohol intake, khat chewing, body mass index (BMI), employment, diabetes, history of asthma, previous history of worm infestation, history of hospitalisation, number of adults living in the household (HH), person per room, housing condition.Results: A total of 312 study participants, including 104 active pulmonary tuberculosis (PTB) cases (cases) and 208 non-active PTB cases (controls), were recruited for the present study. Having one or more family member with a history of TB (OR = 4.4; 95% CI: 1.50–12.90), marital status (OR = 7.6; 95% CI: 2.2–12.6), male gender (OR = 3.2; 95% CI: 1.4–7), rural residence (OR = 3.3; P = 0.012), being a current or past smoker (OR = 2.8; 95% CI: 1.1–7.2), BMI 18.5 (OR = 2.1; 95% CI: 1.03–4.2), HIV infection (OR = 8.8; 95% CI: 2.4–23.8) and a history of worm infestation (OR = 6.4; 95% CI: 2.6–15.4) remained significant independent host-related factors for active PTB.Conclusion: Patients who came from a compound with more than two HHs were more likely to develop active PTB than those who came from a compound with only one HH. Those who lived in houses with no windows were more likely to develop active PTB than those who lived in houses with one or more windows, had a family history of TB, lived in rural areas. Sex of the patient was a predicting factor. Not being the owner of the house was significantly more associated with active PTB. Measures taken to reduce the prevalence and burden of active PTB should consider these determinant factors. Objectifs: Le but de cette étude était de déterminer les Facteurs associés de Tuberculose pulmonaire active à l’Hôpital d’Ambo.Conception: Une étude cas-témoins prospective au sein d’un établissement.Cadre: les patients qui sont venus à l’hôpital d’Ambo du 15 décembre 2011 au 29 mars 2012.Participants: 312 patients adultes sont venus à l’hôpital d’Ambo. Résultats principaux: présence de Tuberculose pulmonaire active.Mesures explicatives: Age, Sexe, Profession, niveau d’études, état civil, lieu de résidence, état tuberculeux du patient, antécédents de Tuberculose, infection VIH, tabagisme, consommation d’alcool, mastication de khât, BMI, emploi, diabète, antécédents d’asthme, antécédents d’infection par des vers, hospitalisations passées, nombre d’adultes vivant au HH, nombre de personnes par chambre, conditions de logement.Résultats: On a recruté 312 participants pour cette étude, 104 cas de Tuberculose pulmonaire active (PTB )et 208 cas de PTB non active (Contrôles). Les patients ayant un membre ou plus de leur famille atteint de Tuberculose (OR = 4.4, 95% CI : 1.50−12.90), les célibataires (OR 7.6, 95% CI : 2.2−12.6), les personnes de sexe masculin (OR 3.2, 95% CI : 1.4–7), les personnes des régions rurales (OR 3.3, p = 0.012), les fumeurs ou anciens fumeurs (OR 2.8, 95% CI : 1.1−7.2), la sous-alimentation (BMI 18.5) (OR 2.1 et 95% CI : 1.03−4.2), l’Infection VIH (OR 8.8 et 95% CI : de 2.4−23.8), les antécédents d’infection de vers (OR 6.4 et 95% CI :2.6−15.4) sont indépendamment des facteurs importants propres aux personnes atteintes de Tuberculose pulmonaire active.Conclusions: les patients provenant d’un composé de plus de deux HH étaient plus susceptibles de développer la Tuberculose pulmonaire active que ceux qui provenaient d’un composé avec un seul HH. Ceux qui vivent dans des maisons sans fenêtres étaient plus susceptibles de développer la Tuberculose pulmonaire active que ceux qui vivent dans des maisons à une fenêtre ou plus. Ceux qui n’étaient pas propriétaire de la maison étaient beaucoup plus susceptibles d’être atteint de Tuberculose pulmonaire active. Les mesures prises pour diminuer la prévalence et le fardeau de la Tuberculose pulmonaire active devraient considérer ces facteurs décisifs.
 
Publisher AOSIS
 
Contributor — —
Date 2015-09-07
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — — —
Format text/html application/octet-stream text/xml application/pdf
Identifier 10.4102/phcfm.v7i1.608
 
Source African Journal of Primary Health Care & Family Medicine; Vol 7, No 1 (2015); 8 pages 2071-2936 2071-2928
 
Language eng
 
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https://phcfm.org/index.php/phcfm/article/view/608/1360 https://phcfm.org/index.php/phcfm/article/view/608/1361 https://phcfm.org/index.php/phcfm/article/view/608/1362 https://phcfm.org/index.php/phcfm/article/view/608/1351
 
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Rights Copyright (c) 2015 Tenna Ephrem, Bezatu Mengiste, Frehiwot Mesfin, Wanzahun Godana https://creativecommons.org/licenses/by/4.0
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