Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi | |
| Creator | Scheepers, E. Leisewitz, A. L. Thompson, P. N. Christopher, M. M. | |
| Description | This prospective longitudinal study investigated the progression of haematological changes in 32 transfused and 54 non-transfused dogs naturally infected with Babesia rossi over the 1st 6 days following diagnosis and treatment. The effect of patient age on the results of complete blood counts was determined. Haematology data were analysed at presentation and at 24 hours, 3 days and 6 days after presentation. Dogs were treated with diminazene aceturate at diagnosis and a blood transfusion was given if deemed clinically required. Mildly to moderately regenerative normocytic normochromic anaemia was observed in all dogs throughout the study period. Transfused dogs more often had an inflammatory leukogram at presentation and at 24 hours, than dogs that were not transfused. In dogs with a left shift, a concurrent normal or decreased segmented neutrophil count was found more commonly than neutrophilia. Severe thrombocytopenia that resolved within a week was common. Blood transfusion alleviated the anaemia, but had no significant effect on white blood cell or platelet responses. Blood cell responses were not significantly influenced by age. In conclusion, the red blood cell and white blood cell responses were less than expected in dogs with babesiosis, given the degree of anaemia and inflammation present. The magnitude of thrombocytopenia and rapid return of the platelet count to normal suggested a possible immune-mediated mechanism for the thrombocytopenia. | |
| Publisher | AOSIS | |
| Date | 2011-04-13 | |
| Identifier | 10.4102/jsava.v82i3.51 | |
| Source | Journal of the South African Veterinary Association; Vol 82, No 3 (2011); 136-143 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/51/57
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