Molecular epidemiology of infectious bursal disease virus in Zambia
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Molecular epidemiology of infectious bursal disease virus in Zambia | |
| Creator | Kasanga, Christopher J. Yamaguchi, Tsuyoshi Munang’andu, Hetron M. Ohya, Kenji Fukushi, Hideto | |
| Description | Nucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 10 infectious bursal disease viruses detected in indigenous and exotic chickens in Zambia from 2004 to 2005 were determined. Phylogenetic analysis showed that the viruses diverged into two genotypes and belonged to the African very virulent types (VV1 and VV2). In the phylogenetic tree, strains in one genotype clustered in a distinct group and were closely related to some strains isolated in western Africa (VV1), with nucleotide similarities of 95.7%– 96.5%. Strains in the other genotype were clustered within the eastern African VV type (VV2), with nucleotide similarities of 97.3%– 98.5%. Both genotypes were distributed in the southern parts of Zambia and had a unique conserved amino acid substitution at 300 (E→A) in addition to the putative virulence marker at positions 222(A), 242(I), 256(I), 294(I) and 299(S). These findings represent the first documentation of the existence of the African VV-IBDV variants in both indigenous and exotic chickens in Zambia. | |
| Publisher | AOSIS | |
| Date | 2013-10-28 | |
| Identifier | 10.4102/jsava.v84i1.908 | |
| Source | Journal of the South African Veterinary Association; Vol 84, No 1 (2013); 4 pages 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/908/1260
https://jsava.co.za/index.php/jsava/article/view/908/1261
https://jsava.co.za/index.php/jsava/article/view/908/1262
https://jsava.co.za/index.php/jsava/article/view/908/1259
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