Interaction of social support and depressive symptoms on antiretroviral therapy adherence among people living with HIV in South Africa
Health SA Gesondheid
| Field | Value | |
| Title | Interaction of social support and depressive symptoms on antiretroviral therapy adherence among people living with HIV in South Africa | |
| Creator | Luthuli, Muziwandile Q. John-Langba, Johannes | |
| Description | Background: Depression consistently emerges as a significant predictor of poor antiretroviral therapy (ART) adherence among adult people living with human immunodeficiency virus (PLHIV). However, a gap exists regarding how social support and depressive symptoms can interact to influence ART adherence among adult PLHIV in South Africa (SA).Aim: To investigate the interaction between social support and depressive symptoms on ART adherence among adult PLHIV.Setting: A tertiary hospital in Durban, KwaZulu-Natal province of SA.Methods: Utilising a quantitative cross-sectional research design along with time location sampling technique (TLS); the study recruited 201 adult patients enrolled in an ART programme.Results: The results indicated that depressive symptoms were significantly associated with ART adherence with and without the interaction (B = -0.105; odds ratios [OR] 0.901; 95% confidence intervals [CI] = 0.827, 0.981; p = 0.016), while social support was not significantly associated with ART adherence (B = 0.007; OR 1.007; 95%CI = 0.989, 1.025; p = 0.475). However, a statistically significant interaction was found between social support and depressive symptoms (B = -0.006; OR 0.994; 95%CI = 0.989, 1.000; p = 0.037) on ART adherence.Conclusion: Based on the results, depressive symptoms significantly influenced ART adherence. However, social support did not buffer the adverse effects of clinical depression associated with poor ART adherence.Contribution: This study provides an evidence-based approach to address gaps in the mental health and social well-being of PLHIV in the context of ART adherence. | |
| Publisher | AOSIS Publishing | |
| Date | 2024-06-06 | |
| Identifier | 10.4102/hsag.v29i0.2271 | |
| Source | Health SA Gesondheid; Vol 29 (2024); 10 pages 2071-9736 1025-9848 | |
| Language | eng | |
| Relation |
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