Diagnostic cut-off value of haemoglobin A1c for diabetes mellitus in Harare, Zimbabwe

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Diagnostic cut-off value of haemoglobin A1c for diabetes mellitus in Harare, Zimbabwe
 
Creator Bvumbi, Chido W. Kouamou, Vinie Kone, Ngalulawa Zaranyika, Trust Bowora, Lloyd Matarira, Hilda T. Chikwati, Raylton P.
 
Subject Medicine; Chemical Pathology; Biochemistry glycated haemoglobin; diabetes mellitus; fasting plasma glucose; receiver operating characteristics curves; Zimbabwe
Description Very little is known about the diagnostic performance of the American Diabetes Association glycated haemoglobin (HbA1c) cut-off of 6.5% in resource-limited settings. This study, conducted between February 2023 and May 2023, aimed to determine the optimal HbA1c cut-off for the diagnosis of diabetes mellitus by measuring HbA1c and fasting plasma glucose levels in 120 adults attending care at a tertiary hospital in Harare, Zimbabwe. The optimal HbA1c cut-off was 6.1% and glucose levels were strongly correlated with HbA1c values. The prevalence of diabetes mellitus was higher (28.3%) at our derived HbA1c cut-off than with the American Diabetes Association criterion (21.6%).What this study adds: This study highlights the need for population-specific cut-off HbA1c values in the diagnosis of diabetes mellitus
 
Publisher AOSIS
 
Contributor
Date 2024-04-23
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross-sectional study
Format text/html application/epub+zip text/xml application/pdf application/pdf
Identifier 10.4102/ajlm.v13i1.2373
 
Source African Journal of Laboratory Medicine; Vol 13, No 1 (2024); 5 pages 2225-2010 2225-2002
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://ajlmonline.org/index.php/ajlm/article/view/2373/2869 https://ajlmonline.org/index.php/ajlm/article/view/2373/2870 https://ajlmonline.org/index.php/ajlm/article/view/2373/2871 https://ajlmonline.org/index.php/ajlm/article/view/2373/2873 https://ajlmonline.org/index.php/ajlm/article/view/2373/2872
 
Coverage Harare; Zimbabwe Current Adult; Male and Female; Black
Rights Copyright (c) 2024 Chido W. Bvumbi, Vinie Kouamou, Ngalulawa Kone, Trust Zaranyika, Lloyd Bowora, Hilda T. Matarira, Raylton P. Chikwati https://creativecommons.org/licenses/by/4.0
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