A laboratory-based study of COVID-19 in Casablanca, Morocco

Journal of Public Health in Africa

Field Value
Title A laboratory-based study of COVID-19 in Casablanca, Morocco
Creator Diawara, Idrissa Benrahma, Houda Meskaouni, Nida Rahoui, Jalila Moujid, Fatima-Zahra Jaras, Khadija Benmessaoud, Rachid Arouro, Khadija Aadam, Zahra Nahir, Salma Aouzal, Zineb Elguazzar, Hajar Jeddan, Leila Rida, Hind Ousti, Fadoua Bakkouri, Jalila E. Smyej, Imane Nejjari, Chakib
Subject — COVID-19; SARS-CoV-2; risk factors; laboratory test; RT-PCR
Description Given the spread of coronavirus disease 2019 (COVID-19) and its impact on human health, laboratory confirmation of diagnosis is essential. This study examined the contribution of laboratory diagnosis to the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the diagnosis of COVID-19, taking into account patient risk of exposure to SARS-CoV-2, clinical symptoms and comorbidities. A cross-sectional, laboratory-based study was carried out from 1 April 2020 to 30 April 2020 at the National Reference Laboratory in Morocco using nasopharyngeal samples from patients admitted to the Cheikh Khalifa International University Hospital or other hospitals in Casablanca. A one-step reverse transcription real-time polymerase chain reaction (RT-PCR) was used to detect the presence of the SARS-CoV-2 genome. A national epidemiological investigation form was used to analyze patient exposure risk, clinical symptoms and comorbidities. A total of 793 samples from 375 patients were analyzed and 1150 RT-PCR tests were conducted; 116 patients (30.93%) were COVID-19 positive. Travel to a risk zone, contact with a confirmed COVID-19 case and contact with a person who had been in a risk zone were significantly associated with being positive for COVID-19. Fever and cough were the main symptoms; 7.76 % of positive patients were asymptomatic. This is the first laboratory-based study in Morocco for the diagnosis of COVID-19. Laboratory diagnosis of COVID-19 by RTPCR associated with knowledge of exposure risk factors and clinical symptoms and comorbidities remains essential for clinicians for early, appropriate medical management COVID-19 patients.
Publisher AOSIS
Date 2021-12-31
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format application/pdf
Identifier 10.4081/jphia.2021.1458
Source Journal of Public Health in Africa; Vol 12, No 2 (2021); 5 2038-9930 2038-9922
Language eng
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Rights Copyright (c) 2024 Idrissa Diawara, Houda Benrahma, Nida Meskaouni, Jalila Rahoui, Fatima-Zahra Moujid, Khadija Jaras, Rachid Benmessaoud, Khadija Arouro, Zahra Aadam, Salma Nahir, Zineb Aouzal, Hajar Elguazzar, Leila Jeddan, Hind Rida, Fadoua Ousti, Jalila E. Bakkouri, Imane Smyej, Chakib Nejjari https://creativecommons.org/licenses/by/4.0