A scoping review on natural cholesterol lowering supplements sold in South African pharmacies

Health SA Gesondheid

Field Value
Title A scoping review on natural cholesterol lowering supplements sold in South African pharmacies
Creator Lee, Hyeon Bok Khan, Razeeya Vally, Muhammed Orchard, Ané
Subject Pharmacy; nutraceuticals LDL; HDL; natural supplements; cholesterol, dyslipidaemia
Description Background: Dyslipidaemia is defined as elevated total or low-density lipoprotein (LDL) levels or low levels of high-density lipoprotein (HDL). Patients may often make use of natural cholesterol lowering supplements (NCLSs) available at the pharmacy; however, limited information on these supplements is readily available. Pharmacists should be knowledgeable about NCLSs to ensure that the use of these supplements is supported by evidence and to provide appropriate advice to patients for desirable therapeutic outcomes.Aim: This study aimed to identify the NCLSs being sold in South African pharmacies and review the scientific evidence for each of the ingredients in these NCLSs.Methods: Seventeen NCLS products were identified, and the Joanna Briggs Institute (JBI) scoping review methodology was used to conduct a literature review of NCLSs.Results: From the ingredients reviewed it is evident that co-enzyme Q10, probiotics and sterols have sufficient evidence supporting their use. However, there is still limited scientific evidence available to validate the remaining ingredients.Conclusion: Further research on NCLSs will provide practising pharmacists and practitioners with a guide of the evidence available on the various ingredients in NCLSs.Contribution: This study provides a review of the available literature on the NCLSs being sold in the pharmacies across South Africa to provide pharmacists with a collated document of the evidence behind these popular supplements to assist them in making evidence based informed decision regarding natural products for cholesterol.
Publisher AOSIS Publishing
Contributor University of the Witwatersrand
Date 2024-02-29
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf application/pdf
Identifier 10.4102/hsag.v29i0.2299
Source Health SA Gesondheid; Vol 29 (2024); 12 pages 2071-9736 1025-9848
Language eng
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Coverage South Africa 2021-2022 NA
Rights Copyright (c) 2024 Hyeon Bok Lee, Razeeya Khan, Muhammed Vally, Ané Orchard https://creativecommons.org/licenses/by/4.0