COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults

Health SA Gesondheid

Field Value
Title COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
Creator Gengiah, Tanuja N. Naidoo, Donavan C. Maduma, Nomcebo Govender, Saien Dhindayal, Sherishka Lewis, Lara
Subject medicine; public health COVID-19; vaccine; hesitancy; vaccination; survey; South Africa.
Description Background: Concerns and misconceptions surrounding coronavirus disease 2019 (COVID-19) vaccines may account for vaccine hesitancy and low uptake.Aim: To determine prevalence of COVID-19 vaccine hesitancy, vaccine-related misconceptions, and predictors of vaccine hesitancy among South Africans.Setting: Community setting in five districts in KwaZulu- Natal province.Methods: Between August 20, 2021, and September 27, 2021, we conducted a cross-sectional survey, interviewing 300 unvaccinated adults amid the national vaccination campaign. Predictors of hesitancy were identified through multivariable logistic regression analysis.Results: Participants had a median age of 29 years (IQR: 23–39), 86.7% were Black African, 63.2% were male, 53.3% resided in rural communities, and 59.3% (95% CI: 53.8% – 64.9%) were classified as vaccine hesitant. The primary reason for not vaccinating was a lack of trust in the vaccine (62.1%). Factors associated with reduced vaccine hesitancy included age (participants aged 35–49 years: OR: 0.28, 95% CI: 0.18–0.64, p = 0.003; participants over 50 years: OR: 0.18, 95% CI: 0.07–0.47, p = 0.0004), previous COVID-19 infection (OR: 0.31, 95% CI: 0.11–0.87, p = 0.03), and receiving vaccine information from healthcare workers (OR: 0.32, 95% CI: 0.10–1.0, p = 0.05). Unemployed (OR: 2.14, 95% CI: 1.1–4.2, p = 0.03) and self-employed individuals (OR: 2.98, 95% CI: 1.27–7.02, p = 0.01) were more likely to be vaccine hesitant.Conclusion: COVID-19 vaccine hesitancy rates are high in KwaZulu-Natal. Uptake could be enhanced by healthcare workers leading information campaigns with messages targeting younger individuals, the unemployed, and the self-employed.Contribution: This survey provides evidence to improve COVID-19 vaccination uptake in South Africa.
Publisher AOSIS Publishing
Contributor Center for the AIDS Programme of Research in South Africa (CAPRISA)
Date 2024-02-01
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross-sectional survey
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/hsag.v29i0.2468
Source Health SA Gesondheid; Vol 29 (2024); 8 pages 2071-9736 1025-9848
Language eng
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Coverage South Africa 20 August – 27 September 2021 Age; gender; ethnicity; language; education; occupation; residence
Rights Copyright (c) 2024 Tanuja N. Gengiah, Donavan C. Naidoo, Nomcebo Maduma, Saien Govender, Sherishka Dhindayal, Lara Lewis