Impact of potassium test sample rejections on routine laboratory service, South Africa

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Impact of potassium test sample rejections on routine laboratory service, South Africa
 
Creator McAlpine, Sarah Chale-Matsau, Bettina
 
Subject Chemical Pathology; Clinical Chemistry; Laboratory Medicine hyperkalaemia; pseudohyperkalaemia; pre-analytical factors; result rejection; sample rejection
Description Background: Accurate potassium measurements are necessary for effective clinical management of hyperkalaemia. Pre-analytical factors may affect laboratory measurements, leading to erroneous results and inappropriate patient management and negatively impact the efficiency and finances of laboratories and hospitals.Objective: This study evaluated the impact of rejected potassium test requests on laboratory service.Methods: We conducted a retrospective descriptive study to assess potassium test data at a public laboratory in Pretoria, Gauteng, South Africa, using samples collected from an academic hospital, peripheral hospitals, and outpatient clinics between January 2018 to December 2018. We assessed the relationship between reasons for rejection and health facility type, as well as financial implications for the laboratory.Results: The potassium result rejection rate was 15.1% (29 806 samples), out of the 197 405 requests received. The most common reasons for rejection were old sample ( 1 day old) (41.4%; 12 348 rejections) and haemolysis (38.2%; 11 398 rejections). The most frequent reason for rejections at the central, academic hospital was haemolysis (42.0%), while old sample was the most common reason for rejection at peripheral hospitals (43.4%; 4119/9493 requests) and outpatient health facilities (57.2%; 7208/12 605 requests) (p = 0.022). The total cost of potassium sample rejection over the study period was substantial, given the resource constraints in this setting.Conclusion: Peripheral hospitals and outpatient departments accounted for the majority of rejected potassium testing results, possibly resulting from delays in transportation; causing substantial financial impact on the laboratory. Improved sample collection, handling, and expedited transportation are recommended.What this study adds: This study highlights the importance of appropriate sample collection and handling and the undesirable consequences of non-adherence to these pre-analytical considerations.
 
Publisher AOSIS
 
Contributor
Date 2023-12-22
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v12i1.2239
 
Source African Journal of Laboratory Medicine; Vol 12, No 1 (2023); 6 pages 2225-2010 2225-2002
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://ajlmonline.org/index.php/ajlm/article/view/2239/2817 https://ajlmonline.org/index.php/ajlm/article/view/2239/2818 https://ajlmonline.org/index.php/ajlm/article/view/2239/2819 https://ajlmonline.org/index.php/ajlm/article/view/2239/2820
 
Coverage — — —
Rights Copyright (c) 2023 Sarah McAlpine, Bettina Chale-Matsau https://creativecommons.org/licenses/by/4.0
ADVERTISEMENT