Vitamin D supplementation in a post-pandemic era: A narrative review

South African Family Practice

Field Value
Title Vitamin D supplementation in a post-pandemic era: A narrative review
Creator Bopape, Pheagane G. Wagenaar, Chrisna Poka, Madan Bronkhorst, Elmien
Subject — vitamin D; COVID-19; chronic diseases; deficiency; calcifediol; cholecalciferol
Description Vitamin D is a fat-soluble molecule referring to the different isoforms, ergocalciferol (D2) and cholecalciferol (D3). Its physiological functions include increasing calcium serum concentrations. 25-hydroxyvitamin D3 (25(OH)D) (Calcifediol), a non-active, circulating instant precursor is seen as a pre-hormone. Studies have shown that a deficiency in calcifediol is related to chronic conditions such as cardiovascular, musculoskeletal, immune system, neurological, and anti-neoplastic functions. Vitamin D supplementation has shown its benefit as prophylaxis and treatment during the coronavirus disease 2019 (COVID-19) pandemic and an increase in the prescribing of vitamin D supplementation has been observed. The intention of this review article is to provide guidance on the recommended dosage regimen as a prophylactic measure during COVID-19 and its use as a supplement in general. From this review article, it is clear that vitamin D has an important role to play not only in COVID-19 but also in various other health aspects of the human body.Contribution: This review article highlighted the role of vitamin D in managing vitamin D deficiency and its role as a supplement in the management of respiratory tract infections, especially COVID-19. This overview can assist physicians in optimising healthcare by optimised dosing recommendations and indications.
Publisher AOSIS
Date 2023-10-17
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Review
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/safp.v65i1.5752
Source South African Family Practice; Vol 65, No 1 (2023): Part 4; 6 pages 2078-6204 2078-6190
Language eng
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Coverage Africa;America;Europe 1998-2022 —
Rights Copyright (c) 2023 Pheagane G. Bopape, Chrisna Wagenaar, Madan Poka, Elmien Bronkhorst