Type 2 diabetes mellitus, physical activity, yoga and telomere length: A literature review
Journal of Metabolic Health (previously Journal of Insulin Resistance)
| Field | Value | |
| Title | Type 2 diabetes mellitus, physical activity, yoga and telomere length: A literature review | |
| Creator | Ughreja, Reepa A. Ughreja, Reena A. | |
| Description | Background: Type 2 diabetes mellitus (DM), a chronic metabolic disease prevalent in adults, is also prevalent amongst children, adolescents and young adults. On understanding the molecular basis of diabetes, a significant association is found between telomere length (TL) and type 2 DM.Aim: The aim of the study was to review the available evidence on effect of physical activity and yoga on DM including their effect on TL.Setting: The study was conducted in Bangalore.Method: A number of databases such as Google Scholar, PubMed and Cochrane Review were searched for relevant articles using keywords such as ’diabetes’, ‘type 2 DM’, ‘physical activity’, ‘yoga’, ‘TL’ and ‘telomerase activity’. All types of articles were included for the study, such as randomised controlled trial, systematic reviews, literature review and pilot study. Non-English articles were excluded from the study.Results: Studies have demonstrated the effectiveness of yoga and physical exercise in type 2 DM in various ways, such as reducing fasting blood glucose and glycosylated haemoglobin; improving lipid profile, blood pressure and waist-to-hip ratio; reducing inflammatory, oxidative and psychological stress markers; and improving the quality of life of patients. However, limited information is available on the effect of these interventions on TL in type 2 DM and mechanisms involved.Conclusion: Recent studies have shown positive effects of yoga and physical activity on TL. However, there is a dearth of good-quality studies evaluating the effects of yoga on TL in type 2 DM. Future studies need to be conducted with standard treatment protocols, long-term follow-up, appropriate control groups and large sample size. | |
| Publisher | AOSIS | |
| Date | 2019-09-10 | |
| Identifier | 10.4102/jir.v4i1.52 | |
| Source | Journal of Metabolic Health; Journal of Insulin Resistance: Vol 4, No 1, 2019; 9 pages 2960-0391 n/a | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://journalofmetabolichealth.org/index.php/jmh/article/view/52/194
https://journalofmetabolichealth.org/index.php/jmh/article/view/52/193
https://journalofmetabolichealth.org/index.php/jmh/article/view/52/195
https://journalofmetabolichealth.org/index.php/jmh/article/view/52/192
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