Butorphanol with oxygen insufflation improves cardiorespiratory function in field-immobilised white rhinoceros (Ceratotherium simum)

Journal of the South African Veterinary Association

 
 
Field Value
 
Title Butorphanol with oxygen insufflation improves cardiorespiratory function in field-immobilised white rhinoceros (Ceratotherium simum)
 
Creator Haw, Anna Hofmeyr, Markus Fuller, Andrea Buss, Peter Miller, Michele Fleming, Gregory Meyer, Leith
 
Subject Wildlife management; veterinary medicine; anaesthesiology Anaesthesia, hypoxia, hypercapnia, acidaemia, blood gases, opioids, partial-opioid antagonist, butorphanol, oxygen, etorphine
Description Opioid-induced immobilisation results in severe respiratory compromise in the white rhinoceros (Ceratotherium simum). The effectiveness of oxygen insufflation combined with butorphanol in alleviating respiratory depression in free-ranging chemically immobilised white rhinoceroses was investigated. In this prospective intervention study 14 freeranging white rhinoceroses were immobilised with a combination of etorphine, azaperone and hyaluronidase. Six minutes (min) after the animals became recumbent, intravenous butorphanol was administered and oxygen insufflation was initiated. Previous boma trial results were used for comparison, using repeated measures two-way analysis of variance. The initial immobilisation-induced hypoxaemia in free-ranging rhinoceroses (arterial partial pressure of oxygen [PaO2] 35.4 mmHg ± 6.6 mmHg) was similar to that observed in bomaconfined rhinoceroses (PaO2 31 mmHg ± 6 mmHg, n = 8). Although the initial hypercapnia (PaCO2 63.0 mmHg ± 7.5 mmHg) was not as severe as that in animals in the boma trial (79 mmHg ± 7 mmHg), the field-immobilised rhinoceroses were more acidaemic (pH 7.10 ± 0.14) at the beginning of the immobilisation compared with boma-immobilised rhinoceroses (pH 7.28 ± 0.04). Compared with pre-intervention values, butorphanol with oxygen insufflation improved the PaO2 (81.2 mmHg ± 23.7 mmHg, p 0.001, 5 min vs 20 min), arterial partial pressure of carbon dioxide (55.3 mmHg ± 5.2 mmHg, p 0.01, 5 min vs 20 min), pH (7.17 ± 0.11, p 0.001, 5 min vs 20 min), heart rate (78 breaths/min ± 20 breaths/min, p 0.001, 5 min vs 20 min) and mean arterial blood pressure (105 mmHg ± 14 mmHg, p 0.01, 5 min vs 20 min). Oxygen insufflation combined with a single intravenous dose of butorphanol improved oxygenation and reduced hypercapnia and acidaemia in immobilised free-ranging white rhinoceroses.
 
Publisher AOSIS
 
Contributor South African National Research Foundation, the International Rhino Foundation, Disney’s Animal Programs and Environmental Initiatives, SANParks, and the University of the Witwatersrand
Date 2015-08-12
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/octet-stream text/xml application/pdf
Identifier 10.4102/jsava.v86i1.1276
 
Source Journal of the South African Veterinary Association; Vol 86, No 1 (2015); 10 pages 2224-9435 1019-9128
 
Language eng
 
Relation
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https://jsava.co.za/index.php/jsava/article/view/1276/1701 https://jsava.co.za/index.php/jsava/article/view/1276/1702 https://jsava.co.za/index.php/jsava/article/view/1276/1703 https://jsava.co.za/index.php/jsava/article/view/1276/1678
 
Coverage Kruger National Park — —
Rights Copyright (c) 2015 Anna Haw, Markus Hofmeyr, Andrea Fuller, Peter Buss, Michele Miller, Gregory Fleming, Leith Meyer https://creativecommons.org/licenses/by/4.0
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