Chemical composition and antibacterial activity of bee venom against multi-drug resistant pathogens
Onderstepoort Journal of Veterinary Research
| Field | Value | |
| Title | Chemical composition and antibacterial activity of bee venom against multi-drug resistant pathogens | |
| Creator | Gökmen, Tülin G. Yazgan, Hatice Özdemir, Yıldız Sevin, Sedat Turut, Nevin Karahan, Şifa Eşki, Funda Kıvrak, İbrahim Sezer, Osman Ütük, Armağan E. | |
| Description | Bee venom with an antimicrobial effect is a powerful natural product. One of the most important areas where new antimicrobials are needed is in the prevention and control of multi-drug resistant pathogens. Today, antibacterial products used to treat multi-drug resistant pathogen infections in hospitals and healthcare facilities are insufficient to prevent colonisation and spread, and new products are needed. The aim of the study is to investigate the antibacterial effect of the bee venom (BV), a natural substance, on the species of Methicillin resistant Staphylococcus aureus, Vancomycin resistant Enterococcus faecalis, Carbapenem resistant Escherichia coli, Carbapenem resistant Klebsiella pneumoniae and Carbapenem resistant Acinetobacter baumannii. As a result of this study, it was found that MIC90 and MBC90 values ranged from 6.25 μg/mL – 12.5 μg/mL and numbers of bacteria decreased by 4–6 logs within 1–24 h for multi-drug resistant pathogens. In particular, Vancomycin resistant Enterococcus faecalis isolate decreased 6 log cfu/mL at 50 μg/mL and 100 μg/mL concentrations in the first hour. The effective bacterial inhibition rate of bee venom suggests that it could be a potential antibacterial agent for multi-drug resistant pathogens.Contribution: The treatment options of antibiotic-resistant pathogens are a major problem in both veterinary and human medicine fields. We have detected a high antibacterial effect against these agents in this bee venom study, which is a natural product. Apitherapy is a fashionable treatment method all over the world and is used in many areas of health. Bee venom is also a product that can be used as a drug or disinfectant raw material and can fill the natural product gap that can be used against resistant bacteria. | |
| Publisher | AOSIS | |
| Date | 2023-07-20 | |
| Identifier | 10.4102/ojvr.v90i1.2097 | |
| Source | Onderstepoort Journal of Veterinary Research; Vol 90, No 1 (2023); 5 pages 2219-0635 0030-2465 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://ojvr.org/index.php/ojvr/article/view/2097/2516
https://ojvr.org/index.php/ojvr/article/view/2097/2517
https://ojvr.org/index.php/ojvr/article/view/2097/2518
https://ojvr.org/index.php/ojvr/article/view/2097/2519
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