Comparison of 3D-conformal and intensity-modulated radiation therapy for left-sided breast cancer
SA Journal of Oncology
| Field | Value | |
| Title | Comparison of 3D-conformal and intensity-modulated radiation therapy for left-sided breast cancer | |
| Creator | Friedrich-Nel, Hesta Long, Deirdré Phahlamohlaka, Nape M. | |
| Description | Background: We compared 3D-conformal radiation therapy (3D-CRT) and intensity-modulated radiation therapy (IMRT) planning for left-sided post-mastectomy patients.Aim: To compare the dose coverage of the planning target volume (PTV) and dose delivered to organs at risk (OAR) of 3D-CRT and IMRT plans.Setting: Department of Oncology, central South Africa.Methods: Twenty-six archived CT scans of patients with left-sided breast cancer were included. The 3D-CRT and IMRT plans were designed for each patient and compared using the Monaco© planning system (version 5.11.02). Statistical analysis was performed for PTV coverage (V95%, V98%, V105%) and radiation doses to the heart, ipsilateral lung, combined lungs, contralateral breast, and oesophagus.Results: The V98% and V105% target volume dose coverage for the 3D-CRT plans were 67.07% and 0.21%, respectively, compared to 92.32% and 1.10% of the IMRT plans. However, the IMRT plans’ mean volume of PTV, receiving 95% of the prescribed dose (PD), was 7.68% compared to the 3D-CRT’s 32.93%. The IMRT plans resulted in a V22 Gy 10% for the heart, with a value of 4.15%. The V18.87 Gy 45% values for the ipsilateral and combined lungs were 28.09% and 13.70%, respectively. The 3D-CRT plans showed a lower dose to the oesophagus (5.07 Gy) and contralateral breast (V5 Gy 15% = 3.51%).Conclusion: It was shown that 3D-CRT and IMRT treatment planning can effectively achieve clinical goals for post-mastectomy left-sided breast cancer radiotherapy.Contribution: The findings underscore the continuing relevance of 3D-CRT planning in oncology for optimal PTV dose coverage and low OAR dose. | |
| Publisher | AOSIS | |
| Date | 2023-06-09 | |
| Identifier | 10.4102/sajo.v7i0.262 | |
| Source | South African Journal of Oncology; Vol 7 (2023); 8 pages 2523-0646 2518-8704 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajo.org.za/index.php/sajo/article/view/262/756
https://sajo.org.za/index.php/sajo/article/view/262/757
https://sajo.org.za/index.php/sajo/article/view/262/758
https://sajo.org.za/index.php/sajo/article/view/262/759
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