Pleurostylia capensis Turcz (Loes): A review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses

Journal of Medicinal Plants for Economic Development

 
 
Field Value
 
Title Pleurostylia capensis Turcz (Loes): A review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses
 
Creator Thembane, Nokukhanya E.
 
Subject — Pleurostylia capensis; phytochemistry; pharmacology; toxicology; ethnomedicine.
Description Background: Pleurostylia capensis Turcz (Loes) is a tree species found in Africa that has been used in traditional medicine for various ailments.Aim: This review aims to investigate the phytochemistry, pharmacology and toxicity of P. capensis Turcz (Loes) and its ethnomedicinal uses.Method: A comprehensive search was conducted using electronic databases, including PubMed, Scopus and Web of Science. The keywords used were ‘Pleurostylia capensis’, ‘phytochemistry’, ‘pharmacology’, ‘toxicology’ and ‘ethnomedicine’. Studies were included if they reported on the phytochemical composition, pharmacological activities, toxicological evaluations and/or ethnomedicinal uses of Pleurostylia capensis.Results: A phytochemical analysis revealed the presence of various bioactive compounds including alkaloids, flavonoids, terpenoids and phenolic compounds. Pharmacological studies have reported the plant’s potential as an anti-inflammatory, antioxidant, antimicrobial and a potential agent for bone and articular cartilage regeneration. Toxicological evaluations have shown that the plant is safe for human consumption at recommended doses.Conclusion: The review highlights the potential of Pleurostylia capensis as a source of bioactive compounds with pharmacological activities. Toxicological evaluations have also shown that the plant is safe for human consumption. The review provides useful information for further research on the development of new drugs from natural products.Contribution: This review provides a comprehensive summary of the phytochemistry, pharmacology, toxicology of Pleurostylia capensis and its ethnomedicinal uses. The review highlights the potential of the plant as a source of bioactive compounds and provides a basis for further research on the development of new drugs from natural products.
 
Publisher AOSIS Publishing
 
Contributor N/A
Date 2023-05-18
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Review
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jomped.v7i1.187
 
Source Journal of Medicinal Plants for Economic Development; Vol 7, No 1 (2023); 6 pages 2616-4809 2519-559X
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://jomped.org/index.php/jomped/article/view/187/621 https://jomped.org/index.php/jomped/article/view/187/622 https://jomped.org/index.php/jomped/article/view/187/623 https://jomped.org/index.php/jomped/article/view/187/624
 
Coverage Africa N/A Literature
Rights Copyright (c) 2023 Nokukhanya E. Thembane https://creativecommons.org/licenses/by/4.0
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