Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele

Onderstepoort Journal of Veterinary Research

Field Value
Title Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele
Creator Magadu, Rungano Thompson, Peter N.
Subject Veterinary Epidemiology; Infectious disease seroprevalence; Coxiella burnetii; goats; ELISA; risk factors; zoonosis
Description Infection with Coxiella burnetii causes significant economic impact and poses zoonotic risk to people exposed to livestock, yet few studies in South Africa have assessed seroprevalence of C. burnetii infection and no information is available for goats. Very little information is available regarding risk factors and outcomes of C. burnetii infection in peri-urban farming areas where widespread mixing of ruminants occurs. This study estimated the seroprevalence of C. burnetii infection among communally farmed goats in an area adjacent to the densely populated Gauteng province. Sera were collected from 216 goats in 39 herds, and questionnaires were completed to establish management practices as potential risk factors. C. burnetii antibody testing was done by ELISA. Thirty two out of 216 goats tested positive for C. burnetii antibodies and the overall seroprevalence, adjusted for sampling weights and clustering, was 18.4% (95% confidence interval [CI]: 12.2% – 23.5%). The intraclass correlation coefficient was 0.06, indicating low-to-moderate clustering. Multiple logistic regression showed age was significantly associated with seropositivity, with higher seroprevalence in animals ≥ 19 months old (26%) than animals ≤ 6 months old (6%) (odds ratio [OR]: 6.6; p = 0.010). We concluded C. burnetii infection is common in goats in Moretele and a potential cause of abortion in goats and poses the potential zoonotic disease risk.Contribution: Despite the threats posed on animal health and productivity, scant information is published on C. burnetii in South Africa. This research established preliminary estimates of C. burnetii seroprevalence. The research is original from a South African perspective, relevant to Africa and focused on infectious disease in livestock.
Publisher AOSIS
Contributor Rungano Magadu Peter Thompson
Date 2023-04-04
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross sectional study
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ojvr.v90i1.2071
Source Onderstepoort Journal of Veterinary Research; Vol 90, No 1 (2023); 7 pages 2219-0635 0030-2465
Language eng
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
Coverage North West province, South Africa — Blood sampling; questionnaire
Rights Copyright (c) 2023 Rungano Magadu, Peter N. Thompson