The effects of corticosteroids and nonsteroidal anti-inflammatory drugs, including aspirin, on coagulation
South African Family Practice
Field | Value | |
Title | The effects of corticosteroids and nonsteroidal anti-inflammatory drugs, including aspirin, on coagulation | |
Creator | Hodgson, Eric | |
Description | The immune and coagulation systems have numerous interactions, as evidenced by the increased risk of venous thromboembolism in inflammatory bowel disease. In general, proinflammatory states are prothrombotic, while a reduction in inflammation reduces thrombotic risk. Corticosteroids, such as hydrocortisone and prednisone, tend to reduce inflammation and thus thrombosis, while being prothrombotic in non-inflammatory states, e.g. Cushing’s syndrome. The nonsteroidal anti-inflammatory drugs also have a dual effect, through interaction with different cyclo-oxygenase enzyme isoforms, on platelets and the vascular endothelium. | |
Publisher | AOSIS | |
Date | 2015-09-01 | |
Identifier | 10.4102/safp.v57i5.4354 | |
Source | South African Family Practice; Vol 57, No 5 (2015): September/October; 3 2078-6204 2078-6190 | |
Language | eng | |
Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://safpj.co.za/index.php/safpj/article/view/4354/5198
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