The effects of corticosteroids and nonsteroidal anti-inflammatory drugs, including aspirin, on coagulation

South African Family Practice

 
 
Field Value
 
Title The effects of corticosteroids and nonsteroidal anti-inflammatory drugs, including aspirin, on coagulation
 
Creator Hodgson, Eric
 
Subject — coagulation; corticosteroids; nonsteroidal anti-inflammatory drugs; NSAIDs
Description The immune and coagulation systems have numerous interactions, as evidenced by the increased risk of venous thromboembolism in inflammatory bowel disease. In general, proinflammatory states are prothrombotic, while a reduction in inflammation reduces thrombotic risk. Corticosteroids, such as hydrocortisone and prednisone, tend to reduce inflammation and thus thrombosis, while being prothrombotic in non-inflammatory states, e.g. Cushing’s syndrome. The nonsteroidal anti-inflammatory drugs also have a dual effect, through interaction with different cyclo-oxygenase enzyme isoforms, on platelets and the vascular endothelium.
 
Publisher AOSIS
 
Contributor
Date 2015-09-01
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article —
Format application/pdf
Identifier 10.4102/safp.v57i5.4354
 
Source South African Family Practice; Vol 57, No 5 (2015): September/October; 3 2078-6204 2078-6190
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://safpj.co.za/index.php/safpj/article/view/4354/5198
 
Coverage — — —
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