Factors influencing treatment adherence in hypertension and HIV management in South Africa: A comparative literature review

South African Family Practice

Field Value
Title Factors influencing treatment adherence in hypertension and HIV management in South Africa: A comparative literature review
Creator Enslin, Dimitra Mallya, Prabhakar
Subject primary health care; education; family medicine; internal medicine; general practice hypertension; adherence; compliance; HIV; counselling; health knowledge; patient education
Description Background: Hypertension (HTN) is the most significant risk factor for cardiovascular disease (CVD) in South Africa (SA), with one in three people over the age of 25 suffering from HTN. Whilst human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) are the leading causes of death in South Africa, CVD is in the top 10 causes of death, demonstrating the importance of detecting and controlling blood pressure early on. This study aimed to review adherence factors to antihypertensive medication and antiretroviral therapy (ART) and evaluate the resulting factors influencing adherence discrepancies within the South African population.Methods: A comprehensive literature review was carried out. PubMed, ScienceDirect, Cochrane and Embase were searched for English publications between 2000 and 2021.Results: A total of 50 articles covering quantitative and qualitative studies were included. Many studies identified poor adherence levels to antihypertensive treatment, reaching a substandard adherence rate of 41.9%, whilst most studies on the HIV-positive population reported good levels of adherence, with adherence rates of more than 90%. Being of the male gender, advanced age, low socioeconomic status and a low level of education were associated with unsatisfactory adherence rates in both groups. Within the HIV group, more participants had better knowledge concerning the extent of their disease and its required treatments.Conclusion: The results present substandard adherence levels to antihypertensives compared with antiretroviral (ARV) adherence, despite the influence of more non-adherence factors in the HIV group. The authors recommend better adherence counselling for patients with HTN during every clinic visit, regular healthcare worker training and the implementation of ART adherence programmes in patients with hypertension.
Publisher AOSIS
Contributor University of South Wales Department of Life Sciences and Education
Date 2022-06-29
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Literature Review
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/safp.v64i1.5434
Source South African Family Practice; Vol 64, No 1 (2022): Part 3; 10 pages 2078-6204 2078-6190
Language eng
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://safpj.co.za/index.php/safpj/article/view/5434/7421 https://safpj.co.za/index.php/safpj/article/view/5434/7422 https://safpj.co.za/index.php/safpj/article/view/5434/7423 https://safpj.co.za/index.php/safpj/article/view/5434/7424
Coverage South Africa 2000-2021 adults; persons living with HIV; hypertensive persons
Rights Copyright (c) 2022 Dimitra Enslin, Prabhakar Mallya https://creativecommons.org/licenses/by/4.0