Theoretical origin of genetically homologous Plasmodium vivax malarial recurrences

Southern African Journal of Infectious Diseases

 
 
Field Value
 
Title Theoretical origin of genetically homologous Plasmodium vivax malarial recurrences
 
Creator Markus, Miles B.
 
Subject Infectious Diseases; Parasitology; Malaria epidemiology; genotyping; hypnozoite; identity by descent; meiotic sibling; Plasmodium vivax; primaquine; relapse; single-cell sequencing; whole-genome sequencing
Description Malaria caused by Plasmodium vivax is being diagnosed with increasing frequency in Africa. Some southern countries where it has been detected are Angola, Botswana, Mozambique, Namibia, Zambia and Zimbabwe. Knowing the parasite origin of P. vivax infection recurrences (which can be reinfections, recrudescences or relapses) is important epidemiologically for malaria elimination in Africa. Although hypnozoites will no doubt be a source, we should try to determine how frequently the origin of non-reinfection recurrences of P. vivax malaria involving closely related parasites may be non-circulating merozoites rather than hypnozoites.
 
Publisher AOSIS Publishing
 
Contributor
Date 2022-03-30
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Academic Analysis
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajid.v37i1.369
 
Source Southern African Journal of Infectious Diseases; Vol 37, No 1 (2022); 2 pages 2313-1810 2312-0053
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajid.co.za/index.php/sajid/article/view/369/912 https://sajid.co.za/index.php/sajid/article/view/369/913 https://sajid.co.za/index.php/sajid/article/view/369/914 https://sajid.co.za/index.php/sajid/article/view/369/915
 
Coverage Global; Worldwide — —
Rights Copyright (c) 2022 Miles Berkeley Markus https://creativecommons.org/licenses/by/4.0
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