Case study: New onset of neuropsychiatric symptoms following switching to a dolutegravir regimen

South African Journal of Psychiatry

 
 
Field Value
 
Title Case study: New onset of neuropsychiatric symptoms following switching to a dolutegravir regimen
 
Creator Badat, Ahmed Lowton, Karishma
 
Subject Psychiatry neuropsychiatric symptoms; dolutegravir; side effects; regimens; monitoring; switching of treatment
Description Although reports of neuropsychiatric side effects have been reported with efavirenz, these have been limited in comparison with regard to the now recommended dolutegravir regimens. We present a patient with new onset neuropsychiatric manifestations secondary to dolutegravir that resulted in significant physical injuries. The patient was initiated on risperidone for symptomatic control which was subsequently weaned and discontinued following reverting to an original efavirenz antiretroviral regimen, with resolution of neuropsychiatric symptoms. Neuropsychiatric side effects are increasingly noted with dolutegravir, and these should be monitored for on initiation and switching of treatment regimens.
 
Publisher AOSIS
 
Contributor
Date 2022-03-29
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — case study
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajpsychiatry.v28i0.1782
 
Source South African Journal of Psychiatry; Vol 28 (2022); 3 pages 2078-6786 1608-9685
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajp.org.za/index.php/sajp/article/view/1782/2571 https://sajp.org.za/index.php/sajp/article/view/1782/2572 https://sajp.org.za/index.php/sajp/article/view/1782/2573 https://sajp.org.za/index.php/sajp/article/view/1782/2574
 
Coverage Gauteng, South Africa — —
Rights Copyright (c) 2022 Ahmed Badat, Karishma Lowton https://creativecommons.org/licenses/by/4.0
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