Evaluation of submaximal endurance in young children living with HIV

South African Journal of Physiotherapy

Field Value
Title Evaluation of submaximal endurance in young children living with HIV
Creator Potterton, Joanne Strehlau, Renate Shiau, Stephanie Comley-White, Nicolette Kuhn, Louise Yin, Michael Arpadi, Stephen
Subject — HIV; children; endurance; physical activity; paediatric
Description Background: There is growing concern about the long-term sequelae [a condition which is the consequence of a previous disease or injury] of perinatally acquired human immunodeficiency virus (HIV). Children living with HIV (CLHIV) present with cardiopulmonary impairments and decreased physical activity which may be due to poor endurance.Objectives: Our study aimed to investigate the sub-maximal endurance of CLHIV compared to a non-infected comparison group.Methods: In this cross-sectional descriptive study 346 CLHIV, between ages five and eleven years, were assessed using the Six Minute Walk Test (6MWT). Blood pressure, heart rate and oxygen saturation were measured pre-test, immediately post-test and five minutes post-test. Clinical and anthropometric data were recorded. Height and weight were assessed using a stadiometer and a digital scale, respectively.Results: 175 CLHIV (52% female) and 171 children without HIV (46% female) participated. All children were Black African. The CLHIV all initiated antiretroviral therapy (ART) at a young age (mean 8.7 months, standard deviation 6.7) and their disease was well controlled (viral load 1000copies/ml). There were no statistically significant differences in submaximal endurance between the two groups (p = 0.831). Age of starting ART and stunted growth were negatively associated (r = -2.8 (p = 0.019) and r = -46.1 (p = 0.027), respectively) with distance walked in the 6MWT by girls living with HIV.Conclusion: CLHIV who initiate ART early with well-controlled disease are able to attain submaximal endurance levels similar to their uninfected peers.Clinical implications: Endurance and physical activity should be monitored in CLHIV. Submaximal endurance levels may improve with age and biological maturation.
Publisher AOSIS
Contributor Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD 073977, HD 073952) National Research Foundation, South Africa.
Date 2022-02-21
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajp.v78i1.1613
Source South African Journal of Physiotherapy; Vol 78, No 1 (2022); 6 pages 2410-8219 0379-6175
Language eng
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https://sajp.co.za/index.php/sajp/article/view/1613/2847 https://sajp.co.za/index.php/sajp/article/view/1613/2848 https://sajp.co.za/index.php/sajp/article/view/1613/2849 https://sajp.co.za/index.php/sajp/article/view/1613/2850
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Rights Copyright (c) 2022 Joanne Potterton, Renate Strehlau, Stephanie Shiau, Nicolette Comley-White, Louise Kuhn, Michael Yin, Stephen Arpadi https://creativecommons.org/licenses/by/4.0