CT pulmonary angiography findings in HIV-infected patients referred for suspected pulmonary thrombo-embolic disease
SA Journal of Radiology
| Field | Value | |
| Title | CT pulmonary angiography findings in HIV-infected patients referred for suspected pulmonary thrombo-embolic disease | |
| Creator | Wiese, Diane Rajkumar, Leisha Lucas, Susan Clopton, David Benfield, Jacob DeBerry, Jason | |
| Description | Background: South Africa bares a significant burden of HIV and imaging is commonly performed as part of the workup for respiratory distress.Objectives: The aim of this study was to document the prevalence of pulmonary thrombo-embolic disease (PTED) and other findings in HIV-infected patients referred for CT pulmonary angiography (CTPA) for suspected PTED.Method: Forty CTPA studies of documented HIV-infected individuals investigated for suspected PTED during a 1-year period were retrieved, anonymised and interpreted by three consultant radiologists. Inter-reader reliability was calculated using Free Marginal multi-rater Kappa.Results: Fourteen of the forty cases (35%) were positive for PTED. In the pulmonary embolism (PE)-positive group, 57.14% had peripheral disease and 42.86% had both peripheral and central disease. Associated findings in the PE-positive cases were pulmonary infarcts (17.5%), mosaic attenuation (17.5%) and linear atelectasis (7.5%). The most common incidental findings were solid pulmonary nodules (52.5%), non-wedge-shaped consolidation (45%), cardiomegaly (52.5%) and enlarged intra-thoracic lymph nodes (52.5%). Thirty per cent of the study population had findings related directly to the presence of PTED, whilst most cases in the study (77.5%) had pulmonary findings unrelated to PTED. In the PE-negative cases, 55% reported emergent findings that warranted immediate or urgent medical attention.Conclusion: Computed tomography pulmonary angiography imaging is critical for diagnosing PE. However, further investigation into the judicious application of CTPA in HIV-infected patients with suspected PTED is required, as CTPA findings in most of the cases in this study were unrelated to PE. | |
| Publisher | AOSIS | |
| Date | 2022-01-31 | |
| Identifier | 10.4102/sajr.v26i1.2273 | |
| Source | South African Journal of Radiology; Vol 26, No 1 (2022); 6 pages 2078-6778 1027-202X | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajr.org.za/index.php/sajr/article/view/2273/3107
https://sajr.org.za/index.php/sajr/article/view/2273/3108
https://sajr.org.za/index.php/sajr/article/view/2273/3109
https://sajr.org.za/index.php/sajr/article/view/2273/3110
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