The pharmacological management of erectile dysfunction – Update 2016

South African Family Practice

 
 
Field Value
 
Title The pharmacological management of erectile dysfunction – Update 2016
 
Creator Marais, André
 
Subject — cardiovascular disease; erectile dysfunction; phosphodiesterase-5 inhibitors; prostaglandin; testosterone
Description Erectile dysfunction (ED) is a trivial condition with a prevailing incidence worldwide. Phosphodiesterase-5 inhibitors (PDE-5) have revolutionised the treatment of ED and are regarded as one of the most successful drug groups in modern medicine. Generally PDE-5 inhibitors are well tolerated and the incidence of side-effects is low, however a small percentage of individuals experience headache, flushing and abdominal discomfort, resulting in discontinuation of therapy. This has led to the development of second generation PDE-5 inhibitors, displaying more selectivity for the PDE-5 enzyme thereby reducing treatment interruption and improving compliance. Several other treatment modalities, including testosterone replacement therapy and prostaglandin administration are available for resistant or failed first-line treatment. This review provides an update on the current, and future, available drugs used in the management of ED.
 
Publisher AOSIS
 
Contributor
Date 2016-08-04
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article —
Format application/pdf
Identifier 10.4102/safp.v58i4.4521
 
Source South African Family Practice; Vol 58, No 4 (2016): July/August; 10-14 2078-6204 2078-6190
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://safpj.co.za/index.php/safpj/article/view/4521/5371
 
Coverage — — —
Rights Copyright (c) 2016 André Marais https://creativecommons.org/licenses/by/4.0
ADVERTISEMENT