Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update

South African Family Practice

 
 
Field Value
 
Title Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
 
Creator Mogole, O. Schellack, N. Motswaledi, M. H.
 
Subject — Steven-Johnsons syndrome (SJS); toxic epidermal necrolysis (TEN); granulysin; supportive care; hypersensitivity; immunomodulating
Description Stevens-Johnson syndrome (SJS) is a form of toxic epidermal necrolysis (TEN) a rare but life-threatening hypersensitivity reactions that affect the skin and mucous membranes. The most common triggers are drugs, but they can also be triggered by infections. Granulysin has been recently identified as the major molecule responsible for the widespread keratinocyte necrosis. Early identification and removal of causative agent is crucial in preventing progression of condition and reducing patient mortality. Supportive care is often recommended over immunomodulating treatments as it helps improve patient outcome.
 
Publisher AOSIS
 
Contributor
Date 2016-11-02
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article —
Format application/pdf
Identifier 10.4102/safp.v58i5.4570
 
Source South African Family Practice; Vol 58, No 5 (2016): September/October; 57-59 2078-6204 2078-6190
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://safpj.co.za/index.php/safpj/article/view/4570/5427 https://safpj.co.za/index.php/safpj/article/downloadSuppFile/4570/1526 https://safpj.co.za/index.php/safpj/article/downloadSuppFile/4570/1527
 
Coverage — — —
Rights Copyright (c) 2016 N. Schellack https://creativecommons.org/licenses/by/4.0
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