Strength exercise for balance and gait in HIV-associated distal symmetrical polyneuropathy: A randomised controlled trial
Southern African Journal of HIV Medicine
| Field | Value | |
| Title | Strength exercise for balance and gait in HIV-associated distal symmetrical polyneuropathy: A randomised controlled trial | |
| Creator | Yakasai, Abdulsalam M. Maharaj, Sonill Danazumi, Musa S. | |
| Description | Background: HIV-associated peripheral neuropathy (PN) is a common neurological complication associated with HIV infection. Distal symmetrical polyneuropathy (DSPN) is the most commonly occurring type, which is associated with symptoms such as numbness, unsteady gait and, in some cases, muscle atrophy and weakness when myelinated nerve fibres are affected. If unmyelinated nerve fibres are affected, a painful neuropathy and autonomic symptoms may occur.Objectives: This research study assessed the effects of a strength exercise intervention on balance impairment and gait disturbance amongst individuals living with HIV-associated DSPN.Method: The study was a single-blinded, randomised controlled trial (RCT) with participants sourced from four HIV centres in Kano metropolis, Nigeria. The intervention was supervised and included progressive resistance exercise (PRE) (three 40-min sessions per week for 12 weeks) using a quadriceps bench (n = 44). The control group (CG) included the non-exercise group (n = 47). The two groups continued to receive routine care. Data were summarised and analysed using inferential statistics (SPSS version 20 program) with the alpha level set at 0.05.Results: At 12 weeks, the results revealed significant improvement with regard to balance performance (p = 0.001) and walking ability (p = 0.001) in the training group. In contrast, no significant differences in balance (P = 0.677) or gait (P = 0.578) were observed in the CG.Conclusion: The findings suggest that PRE is beneficial for balance impairment and gait disturbance caused by neuropathy in persons living with HIV and receiving antiretroviral drugs. | |
| Publisher | AOSIS | |
| Date | 2021-10-05 | |
| Identifier | 10.4102/sajhivmed.v22i1.1268 | |
| Source | Southern African Journal of HIV Medicine; Vol 22, No 1 (2021); 7 pages 2078-6751 1608-9693 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajhivmed.org.za/index.php/hivmed/article/view/1268/2590
https://sajhivmed.org.za/index.php/hivmed/article/view/1268/2591
https://sajhivmed.org.za/index.php/hivmed/article/view/1268/2592
https://sajhivmed.org.za/index.php/hivmed/article/view/1268/2593
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