Wide circulation of peste des petits ruminants virus in sheep and goats across Nigeria

Onderstepoort Journal of Veterinary Research

Field Value
Title Wide circulation of peste des petits ruminants virus in sheep and goats across Nigeria
Creator Mantip, Samuel E. Sigismeau, Anthony Nanven, Maurice Joel, Atuman Qasim, Abayomi M. Aliyu, Sada Musa, Ibrahim Ezeanyika, Ogechukwu Faramade, Ibikunle Ahmed, Garba Woma, Timothy Y. Shamaki, David Libeau, Genevieve Farougou, Souaibou Bataille, Arnaud
Subject Veterinary science; Molecular biology; Virology; Bio-technology; Cell-culture studies Peste des petits ruminants; Nigeria; transboundary animal disease; virus isolation; RT-PCR; morbillivirus; sequencing
Description Peste des petits ruminants (PPR) is a highly contagious viral disease that mainly affects goats and sheep in Asia, Africa and the Middle East, and threatens Europe [R.E.1]. The disease is endemic on the African continent, particularly in West Africa, and is a major factor driving food insecurity in low-income populations. The aim of this research study was to carry out surveillance, genetic characterisation and isolation of recently circulating PPR viruses (PPRV) in sheep and goats from the six agro-ecological zones of Nigeria. A total of 268 post-mortem tissue samples of lung and mesenteric ganglia were collected from clinically suspected sheep and goats in 18 different states, of which five never previously sampled. The presence of PPRV was confirmed using a reverse-transcription coupled with a polymerase chain reaction (RT-PCR) assay. A total of 72 samples, 17 sheep (6%) and 55 goats (21%), were found to be PPR positive. Positive samples were distributed in almost all states, except Kano, where PPR was detected in previous studies. The PPRV-positive samples were further confirmed by sequencing or virus isolation in areas where the infection had never previously been detected. These results confirm the active circulation of PPRV across all six agro-ecological zones of Nigeria, and consequently, the need for introducing strict measures for the control and prevention of the disease in the country.
Publisher AOSIS
Contributor NVRI, Nigeria CIRAD, France European Union
Date 2021-09-07
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Surveilance and molecular analysis
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ojvr.v88i1.1899
Source Onderstepoort Journal of Veterinary Research; Vol 88, No 1 (2021); 7 pages 2219-0635 0030-2465
Language eng
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

info:eu-repo/grantAgreement/EC/FP7/410957 https://ojvr.org/index.php/ojvr/article/view/1899/2276 https://ojvr.org/index.php/ojvr/article/view/1899/2277 https://ojvr.org/index.php/ojvr/article/view/1899/2278 https://ojvr.org/index.php/ojvr/article/view/1899/2279
Coverage All the Six Agro-ecological zones of Nigeria On-set of rainny season Different ages; Male and female; Sheep and goats
Rights info:eu-repo/semantics/openAccess Copyright (c) 2021 Samuel Elias Mantip, Anthony Sigismeau, Maurice Nanven, Atuman Joel, Aliyu Sada, Abayomi Qasim, Ibrahim Musa, Ogechukwu Ezeanyika, Ibikunle Faramade, Garba Ahmed, Timothy Yusufu Woma, David Shamaki, Genevieve Libeau, Souaibou Farougou, Arnaud Bataille https://creativecommons.org/licenses/by-nd/4.0