Associations of premorbid adjustment with type and timing of childhood trauma in first-episode schizophrenia spectrum disorders

South African Journal of Psychiatry


 
 
Field Value
 
Title Associations of premorbid adjustment with type and timing of childhood trauma in first-episode schizophrenia spectrum disorders
 
Creator Smit, Anna M. Kilian, Sanja Emsley, Robin A. Luckhoff, Hilmar K. Swartz, Leslie Seedat, Soraya Asmal, Laila
 
Subject Psychiatry childhood trauma; premorbid adjustment; first episode schizophrenia spectrum disorders; academic and social functioning; early adolescence
Description Background: Childhood trauma may contribute to poorer premorbid social and academic adjustment which may be a risk factor for schizophrenia.Aim: We explored the relationship between premorbid adjustment and childhood trauma, timing of childhood trauma’s moderating role as well as the association of clinical and treatment-related confounders with premorbid adjustment.Setting: We conducted a secondary analysis in 111 patients with first-episode schizophrenia (FES) disorders that formed part of two parent studies, EONKCS study (n =73) and the Shared Roots study (n =38).Methods: Type of childhood trauma was assessed with the Childhood Trauma Questionnaire, short-form and premorbid adjustment using the Premorbid Adjustment Scale. Timing of childhood trauma was assessed using the Life Events Checklist and life events timeline. Linear regression analyses were used to assess the moderating effect of timing of childhood trauma. Clinical and treatment-related confounders were entered into sequential hierarchical regression models to identify independent predictors of premorbid adjustment across key life stages.Results: Childhood physical neglect was associated with poorer premorbid academic functioning during childhood and early adolescence, and poorer premorbid social functioning during early and late adolescence. By hierarchical regression modelling (r2 = 0.13), higher physical neglect subscale scores (p = 0.011) independently predicted poorer premorbid social adjustment during early adolescence. Timing of childhood trauma did not moderate the relationship between childhood trauma and premorbid functioning.Conclusion: In patients with FES, childhood physical neglect may contribute to poorer premorbid social functioning during early adolescence. This may provide us with an opportunity to identify and treat at-risk individuals earlier.
 
Publisher AOSIS
 
Contributor Stellenbosch University, Department of Psychiatry
Date 2021-06-22
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Quantitative research
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajpsychiatry.v27i0.1639
 
Source South African Journal of Psychiatry; Vol 27 (2021); 7 pages 2078-6786 1608-9685
 
Language eng
 
Relation info:eu-repo/grantAgreement/EC/FP7/012013 https://sajp.org.za/index.php/sajp/article/view/1639/2195 https://sajp.org.za/index.php/sajp/article/view/1639/2196 https://sajp.org.za/index.php/sajp/article/view/1639/2197 https://sajp.org.za/index.php/sajp/article/view/1639/2198
 
Coverage Western Cape, South Africa 2005- 2017 age 16 - 45, male and female, first episode schizophrenia spectrum disorders
Rights info:eu-repo/semantics/openAccess Copyright (c) 2021 Anna M. Smit, Sanja Kilian, Robin A. Emsley, Hilmar K. Luckhoff, Leslie Swartz, Soraya Seedat, Laila Asmal https://creativecommons.org/licenses/by/4.0