Ocular manifestations of people living with HIV in Tunisia

Southern African Journal of HIV Medicine

Field Value
Title Ocular manifestations of people living with HIV in Tunisia
Creator Saadouli, Dorsaf Ammari, Lamia Mansour, Khaoula Ben Yahyaoui, Yosra Aissa, Sameh Ali, El Afrit Mohamed Yahyaoui, Salem Tiouri, Hanene
Subject — acquired immunodeficiency syndrome; human immunodeficiency virus; ocular manifestation; uveitis; immune recovery uveitis; cytomegalovirus retinitis
Description Background: Ocular involvement is a common complication of human immunodeficiency virus (HIV). Knowledge about this topic in Tunisia is limited.Objective: To investigate ophthalmic manifestations in patients living with HIV in Tunisia.Method: This was an observational study, performed between January 2007 and December 2016. We included patients with ocular disorders related to HIV. The data were recorded retrospectively from chart review.Results: Amongst 98 people living with HIV (PLWH), 36 participants (55 eyes) had ocular manifestations. The mean age was 32.2 ± 5.6 years. Twenty-four patients were men and 12 were women. The mean value of CD4+ T-cell count was 156.5 ± 4.2 cells/µL. Bilateral lesions were found in 19 eyes. Best corrected visual acuity was better than 6/12 in 36 eyes. The most common ocular finding was dry eye syndrome (22%), cotton-wool spots (20%) and retinal haemorrhage (16%) followed by cytomegalovirus (CMV) retinitis (9%), anterior uveitis (7%), toxoplasmosis (4%) and tuberculosis retinochoroiditis (7%) Herpetic keratitis (5%), Herpes zoster ophthalmicus (2%) and syphilitic chorioretinitis (2%). Papilledema was found in three eyes (5%). Panuveitis was observed in four eyes (7%): three of them were associated with chorioretinal toxoplasmosis, syphilitic chorioretinitis and CMV retinitis. The fourth was attributable to immune recovery uveitis. A CD4+ T-cell count of ≤ 200 cells/µL was found to be an independent risk factor for developing posterior segment manifestations.Conclusion: Various ophthalmic manifestations were observed in PLWH. The most common lesion was retinopathy. Ocular involvement can be serious leading to poor visual prognosis, which requires close collaboration between the ophthalmologist and infectious disease physician.
Publisher AOSIS
Date 2021-03-19
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — retrospective
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajhivmed.v22i1.1193
Source Southern African Journal of HIV Medicine; Vol 22, No 1 (2021); 5 pages 2078-6751 1608-9693
Language eng
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https://sajhivmed.org.za/index.php/hivmed/article/view/1193/2345 https://sajhivmed.org.za/index.php/hivmed/article/view/1193/2344 https://sajhivmed.org.za/index.php/hivmed/article/view/1193/2346 https://sajhivmed.org.za/index.php/hivmed/article/view/1193/2343
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Rights Copyright (c) 2021 Dorsaf Saadouli, Lamia Ammari, Khaoula Ben Mansour, Yosra Yahyaoui, Sameh Aissa, El Afrit Mohamed Ali, Salem Yahyaoui, Hanene Tiouri https://creativecommons.org/licenses/by/4.0