Epstein-Barr virus, human papillomavirus and herpes simplex virus 2 co-presence severely dysregulates miRNA expression

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Epstein-Barr virus, human papillomavirus and herpes simplex virus 2 co-presence severely dysregulates miRNA expression
 
Creator Okoye, Jude O. Ngokere, Anthony A. Onyenekwe, Charles C. Omotuyi, Olaposi Dada, Deborah I.
 
Subject Gynaecology; Oncology; Molecular Biology; Cancer; Virology Epstein-Barr virus; human papilloma virus; herpes simplex virus 2; epithelial-mesenchymal transition; microRNAs
Description This cross-sectional study evaluated the expression of miR-let-7b, miR-21, miR-125b, miR-143, miR-145, miR-155, miR-182, miR-200c, p53 gene, Ki67, SCCA1 and CD4+ T-cell counts among 319 women, to Epstein-Barr virus, human papillomavirus and herpes simplex virus 2 mono-infections and co-infections, using enzyme-linked immunosorbent assay and reverse transcriptase-polymerase chain reaction methods. This study suggests that malignancies associated with viral co-infection could be diagnosed early by monitoring cluster of differentiation 4+ T-cell counts and serum expression of miR-145 and miR-182.
 
Publisher AOSIS
 
Contributor None
Date 2021-03-16
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Cross-sectional survey
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v10i1.975
 
Source African Journal of Laboratory Medicine; Vol 10, No 1 (2021); 10 pages 2225-2010 2225-2002
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://ajlmonline.org/index.php/ajlm/article/view/975/1901 https://ajlmonline.org/index.php/ajlm/article/view/975/1900 https://ajlmonline.org/index.php/ajlm/article/view/975/1902 https://ajlmonline.org/index.php/ajlm/article/view/975/1899
 
Coverage Ogun State, Nigeria — Females
Rights Copyright (c) 2021 Jude O. Okoye, Anthony A. Ngokere, Charles C. Onyenekwe, Olaposi Omotuyi, Deborah I. Dada https://creativecommons.org/licenses/by/4.0
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