Determination of split renal function in voluntary renal donors by multidetector computed tomography and nuclear renography: How well do they correlate?

SA Journal of Radiology


 
 
Field Value
 
Title Determination of split renal function in voluntary renal donors by multidetector computed tomography and nuclear renography: How well do they correlate?
 
Creator Lal, Hira Singh, Anuradha Prasad, Raghunandan Yadav, Priyank Akhtar, Javed Barai, Sukanta Mishra, Prabhakar Bhadauria, Dharmendra Kaul, Anupma Prasad, Narayan Verma, Pragati
 
Subject Radiology; renal transplantation nuclear renography; split renal function; computed tomography; volumetry; attenuation.
Description Background: The use of computed tomography (CT) for estimation of split renal function (SRF) has been reported previously. However, most of these studies have small samples, and many do not account for the renal attenuation at CT.Objective: The aim of this study was to compare multidetector computed tomography (MDCT) volumetry-attenuation-based SRF with that obtained via Tc99m-diethylenetriaminepentaacetic acid (DTPA) renal scintigraphy in voluntary renal donors.Methods: Between January 2017 and January 2020, 526 voluntary renal donors were enrolled prospectively. All donors underwent contrast CT and DTPA scan before surgery. The semiautomatic region of interest (ROI) tool was applied slice by slice on axial CT images acquired in the arterial phase. The renal contour was drawn semiautomatically with mouse clicks around the renal parenchyma, and the renal volume was ascertained. Using renal volume and attenuation, SRF was determined and compared with results obtained at DTPA imaging.Results: The mean age was 44.91 ± 10.97 years (mean ± s.d.). There was no significant difference in SRF based on DTPA and MDCT volumetry for the left kidney (49.18% ± 3.40% vs. 49.15% ± 3.38%, p = 0.540) and for the right kidney (50.82% ± 3.40% vs. 50.86% ± 3.39%, p = 0.358). A very good correlation was observed between the two methods for the left kidney (r = 0.953, p = 0.000) and the right kidney (r = 0.955, p = 0.000). On simple linear regression analysis, 90.8% of DTPA SRF values for the left kidney and 91.3% of DTPA SRF values for the right kidney could be predicted correctly using the corresponding MDCT SRF values.Conclusion: MDCT volumetry-attenuation-derived estimation of SRF for living renal donors could be an alternative to renal scintigraphy-based SRF estimation.
 
Publisher AOSIS
 
Contributor
Date 2021-03-05
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajr.v25i1.2009
 
Source South African Journal of Radiology; Vol 25, No 1 (2021); 8 pages 2078-6778 1027-202X
 
Language eng
 
Relation https://sajr.org.za/index.php/sajr/article/view/2009/2782 https://sajr.org.za/index.php/sajr/article/view/2009/2781 https://sajr.org.za/index.php/sajr/article/view/2009/2783 https://sajr.org.za/index.php/sajr/article/view/2009/2780
 
Coverage South Asia 2017-2020 —
Rights Copyright (c) 2021 Hira Lal, Anuradha Singh, Raghunandan Prasad, Priyank Yadav, Javed Akhtar, Sukanta Barai, Prabhakar Mishra, Dharmendra Bhadauria, Anupma Kaul, Narayan Prasad, Pragati Verma https://creativecommons.org/licenses/by/4.0