Unilateral salpingectomy in Sprague Dawley rats and its effect on litter size

Journal of the South African Veterinary Association

 
 
Field Value
 
Title Unilateral salpingectomy in Sprague Dawley rats and its effect on litter size
 
Creator Bester, Elizabeth G. Schulman, Martin Kirberger, Robert M. Hartman, Marthinus
 
Subject Laboratory; Scientific; Veterinary Medicine salpingectomy; litter size; rat sterilisation; unilateral salpingectomy; placental weights; foetal weights
Description The study described a novel, rapidly performed, successful and safe surgical procedure in rats to achieve a reduction in the number of conceptuses. The objectives were to investigate the total foetal count and foetal health in both uterine horns after unilateral salpingectomy compared to the control group. Sixteen female Sprague-Dawley rats (Rattus norvegicus) were allocated to the study of which 10 rats underwent unilateral salpingectomy with six controls before all 16 were mated at 8–10 weeks of age. Gestational length was taken as 22 days coma? determined from the day of appearance of the copulatory plug. The female rats were terminated on day 19 or 20 of the gestational period. The foetuses in each horn were mapped and counted for comparison between the salpingectomy and control groups. The gravid uteri, individual foetal weights and placental weights were measured and compared between the two groups. This study described a novel, rapidly performed, successful and safe surgical procedure in rats. The mean number of foetuses in the salpingectomy group was significantly smaller than the control group. No significant differences in foetal and placental development were observed between the groups. These observations support future investigation of unilateral salpingectomy in other species as an alternative surgical method for population control.
 
Publisher AOSIS
 
Contributor
Date 2021-01-28
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Quasi- experimental
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/jsava.v92i0.2101
 
Source Journal of the South African Veterinary Association; Vol 92 (2021); 6 pages 2224-9435 1019-9128
 
Language eng
 
Relation
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https://jsava.co.za/index.php/jsava/article/view/2101/2666 https://jsava.co.za/index.php/jsava/article/view/2101/2665 https://jsava.co.za/index.php/jsava/article/view/2101/2667 https://jsava.co.za/index.php/jsava/article/view/2101/2664
 
Coverage — — —
Rights Copyright (c) 2021 Elizabeth Gertruida Bester https://creativecommons.org/licenses/by/4.0
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