Categorising specimen referral delays for CD4 testing: How inter-laboratory distances and travel times impact turn-around time across a national laboratory service in South Africa

African Journal of Laboratory Medicine

 
 
Field Value
 
Title Categorising specimen referral delays for CD4 testing: How inter-laboratory distances and travel times impact turn-around time across a national laboratory service in South Africa
 
Creator Cassim, Naseem Coetzee, Lindi M. Glencross, Deborah K.
 
Subject Health Sciences HIV; cluster of differentiation 4; CD4; immune status; inter-laboratory referral; distance; travel time
Description Background: The South African National Health Laboratory Service provides laboratory services for public sector health facilities, utilising a tiered laboratory model to refer samples for CD4 testing from 255 source laboratories into 43 testing laboratories.Objective: The aim of this study was to determine the impact of distance on inter-laboratory referral time for public sector testing in South Africa in 2018.Methods: A retrospective cross-sectional study design analysed CD4 testing inter-laboratory turn-around time (TAT) data for 2018, that is laboratory-to-laboratory TAT from registration at the source to referral receipt at the testing laboratory. Google Maps was used to calculate inter-laboratory distances and travel times. Distances were categorised into four buckets, with the median and 75th percentile reported. Wilcoxon scores were used to assess significant differences in laboratory-to-laboratory TAT across the four distance categories.Results: CD4 referrals from off-site source laboratories comprised 49% (n = 1 390 510) of national reporting. A positively skewed distribution of laboratory-to-laboratory TAT was noted, with a median travel time of 11 h (interquartile range: 7–17), within the stipulated 12 h target. Inter-laboratory distance categories of less than 100 km, 101–200 km, 201–300 km and more than 300 km (p 0.0001) had 75th percentiles of 8 h, 17 h, 14 h and 27 h.Conclusion: Variability in inter-laboratory TAT was noted for all inter-laboratory distances, especially those exceeding 300 km. The correlation between distance and laboratory-to-laboratory TAT suggests that interventions are required for distant laboratories.
 
Publisher AOSIS
 
Contributor N/A
Date 2020-12-21
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective; Cross sectional
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v9i1.1120
 
Source African Journal of Laboratory Medicine; Vol 9, No 1 (2020); 7 pages 2225-2010 2225-2002
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://ajlmonline.org/index.php/ajlm/article/view/1120/1832 https://ajlmonline.org/index.php/ajlm/article/view/1120/1831 https://ajlmonline.org/index.php/ajlm/article/view/1120/1833 https://ajlmonline.org/index.php/ajlm/article/view/1120/1830
 
Coverage South Africa Chronological Laboratory; Sample; Inter-laboratory referral
Rights Copyright (c) 2020 Naseem Cassim, Lindi Marie Coetzee, Deborah Kim Glencross https://creativecommons.org/licenses/by/4.0
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