Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting

African Journal of Laboratory Medicine


 
 
Field Value
 
Title Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting
 
Creator Newman, Howard Tshabalala, Donald Mabunda, Sikhumbuzo Nkosi, Nokwazi Carelson, Candice
 
Subject Clinical Virology; Laboratory Medicine; Respiratory Viruses respiratory syncytial virus; rapid antigen tests; respiratory viruses; respiratory multiplex polymerase chain reaction; assay performance characteristics
Description We analysed the performance characteristics of the respiratory syncytial virus lateral flow rapid antigen assay in use when compared to a multiplex polymerase chain reaction for detection of respiratory viruses. The study was conducted at a tertiary paediatric hospital in Port Elizabeth, South Africa, from 01 January 2017 to 31 December 2018. We found the clinical sensitivity (36.8%) of the rapid test to be too low for routine diagnostic use. Knowledge of assay performance characteristics of rapid tests are important for appropriate interpretation of rapid test results.
 
Publisher AOSIS
 
Contributor National Health Laboratory Service
Date 2020-12-08
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — retrospective cross-sectional review
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/ajlm.v9i1.1084
 
Source African Journal of Laboratory Medicine; Vol 9, No 1 (2020); 5 pages 2225-2010 2225-2002
 
Language eng
 
Relation https://ajlmonline.org/index.php/ajlm/article/view/1084/1770 https://ajlmonline.org/index.php/ajlm/article/view/1084/1769 https://ajlmonline.org/index.php/ajlm/article/view/1084/1771 https://ajlmonline.org/index.php/ajlm/article/view/1084/1768
 
Coverage — — Paediatrics
Rights Copyright (c) 2020 Howard Newman, Donald Tshabalala, Sikhumbuzo Mabunda, Nokwazi Nkosi, Candice Carelson https://creativecommons.org/licenses/by/4.0