Adult T-cell leukaemia/lymphoma in an adolescent patient: Expect the unexpected
SA Journal of Oncology
| Field | Value | |
| Title | Adult T-cell leukaemia/lymphoma in an adolescent patient: Expect the unexpected | |
| Creator | Abdullah, Ibtisam Nell, Erica-Mari Chapanduka, Zivanai C. | |
| Description | This case study explores a clinicopathological presentation of Adult T-cell leukaemia/lymphoma (ATLL) at Tygerberg Hospital; a disease associated with adulthood noted in an adolescent patient. Adult T-cell leukaemia–lymphoma oncogenesis develops through a multistep process with an accumulation of mutations. Infection through human T-lymphotropic virus type 1 (HTLV-1) is the first step of a multistep process resulting in eventual clonal proliferation of mature T-cells. There is a long latency period of 20–50 years from the time of infection with HTLV-1 to the development of symptoms of ATLL; thus, ATLL is a malignancy associated with adulthood. The median age of diagnosis is 58, ranging from the third to ninth decade of life. This is an ideal learning case as it highlights the importance of recognising ATLL in children and young adults in our population. | |
| Publisher | AOSIS | |
| Date | 2020-05-25 | |
| Identifier | 10.4102/sajo.v4i0.121 | |
| Source | South African Journal of Oncology; Vol 4 (2020); 4 pages 2523-0646 2518-8704 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajo.org.za/index.php/sajo/article/view/121/348
https://sajo.org.za/index.php/sajo/article/view/121/347
https://sajo.org.za/index.php/sajo/article/view/121/349
https://sajo.org.za/index.php/sajo/article/view/121/346
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