The effect of endogenously produced carbon monoxide on the oxygen status of dogs infected with Babesia canis
Journal of the South African Veterinary Association
| Field | Value | |
| Title | The effect of endogenously produced carbon monoxide on the oxygen status of dogs infected with Babesia canis | |
| Creator | Taylor, J. H. Gutherie, A. J. Leisewitz, A. | |
| Description | Carboxyhaemoglobin fractions were found to be significantly higher (p0,05) in dogs (n=5) with severe babesiosis than in control subjects (n=5). The enzymatic conversion of haem to biliverdin by haem oxygenase is the only known source of endogenous carbon monoxide. We propose that the increased production of endogenous carbon monoxide following the haemolysis associated with babesiosis, results in the carboxyhaemoglobinaeroia observed in this study. The superimposition of carboxyhaemoglobinaemia on severe anaemia results in further compromise of the oxygen status of dogs with severe babesiosis, and probably plays a role in the pathogenesis of the hypoxic tissue damage associated with this condition. | |
| Publisher | AOSIS | |
| Date | 1991-12-31 | |
| Identifier | 10.4102/jsava.v62i4.1774 | |
| Source | Journal of the South African Veterinary Association; Vol 62, No 4 (1991); 153-155 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/1774/2142
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