Motor lumbosacral radiculopathy in HIV-infected patients

Southern African Journal of HIV Medicine

 
 
Field Value
 
Title Motor lumbosacral radiculopathy in HIV-infected patients
 
Creator Moodley, Kaminie Bill, Pierre L.A. Patel, Vinod B.
 
Subject Medical HIV; lumbosacral radiculopathy; ART; corticosteroids; treatment outcome
Description Background: This study is a review of the clinical findings and treatment outcome of 11 HIV-infected patients with motor lumbosacral radiculopathy.Objectives: To describe the clinical, laboratory, electrophysiological features and treatment outcome in HIV-infected motor lumbosacral radiculopathy which is a rare manifestation of HIV.Method: A retrospective review of HIV-infected patients with motor lumbosacral radiculopathy was performed at Inkosi Albert Luthuli Central Hospital (IALCH), Durban, South Africa between 2010 and 2015.Results: Eleven black African patients met the inclusion criteria. There were six women. The median age was 29 years, the interquartile range (IQR) was 23–41 years, the median duration of symptom progression was 6.5 months (IQR 3–7.5 months). The median CD4 count was 327 cells/µL (IQR 146–457). The cerebrospinal fluid (CSF) median polymorphocyte count was 0 cells/µL (IQR 0 cells/µL – 2 cells/µL), lymphocyte count was 16 cells/µL (IQR 1 cells/µL – 18 cells/µL), glucose level was 3.1 mmol/L (IQR 2.8 mmol/L – 3.4 mmol/L) and protein level was 1.02 g/dL (IQR 0.98 g/dL – 3.4 g/dL). All patients were treated with corticosteroid therapy. Ninety-one per cent recovered fully within 6 months of treatment, the median time for recovery was 3.4 months (IQR 1.8–5.6 months). There were no relapses during the 18-month follow-up.Conclusion: HIV-infected patients with motor lumbosacral radiculopathy responded to corticosteroids, with no relapses during the 18-month follow-up period.
 
Publisher AOSIS
 
Contributor Pierre L.A. Bill, Vinod B. Patel
Date 2019-10-28
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — Retrospective
Format text/html application/epub+zip text/xml application/pdf
Identifier 10.4102/sajhivmed.v20i1.992
 
Source Southern African Journal of HIV Medicine; Vol 20, No 1 (2019); 6 pages 2078-6751 1608-9693
 
Language eng
 
Relation
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:

https://sajhivmed.org.za/index.php/hivmed/article/view/992/1669 https://sajhivmed.org.za/index.php/hivmed/article/view/992/1668 https://sajhivmed.org.za/index.php/hivmed/article/view/992/1670 https://sajhivmed.org.za/index.php/hivmed/article/view/992/1667
 
Coverage KwaZulu Natal 2010-2015 Older than 18 yrs, male and female, no ethnic restrictions
Rights Copyright (c) 2019 Kaminie Moodley, Pierre L.A. Bill, Vinod B. Patel https://creativecommons.org/licenses/by/4.0
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