Interferon alpha in subacute sclerosing panencephalitis: Case report and review of the literature
Southern African Journal of Infectious Diseases
| Field | Value | |
| Title | Interferon alpha in subacute sclerosing panencephalitis: Case report and review of the literature | |
| Creator | Moodley, K. Bill, P. L. A. Patel, V. B. | |
| Description | Subacute Sclerosing Panencephalitis (SSPE) is a rare, rapidly progressive neurodegenerative disease caused by the measles virus. Spontaneous remission and survival longer than 4 years is rare. The disease commonly affects children and adolescents from less privileged socio-economic backgrounds. Prior to immunisation, the incidence of SSPE in South Africa (SA) was 2.6/100 000 people per year, which is higher than the global estimate of 1/1 000 000 per year. The post-immunisation incidence has dropped to 0.43/100 000 people per year. Currently, there is no curative treatment for SSPE. In developed countries, patients have been treated with antiviral therapy and interferon alpha (IFNα) with promising results. There have been no reported studies of children with SSPE treated with IFNα in South Africa. We report on a patient successfully treated with intraventricular INFα. | |
| Publisher | AOSIS Publishing | |
| Date | 2016-12-31 | |
| Identifier | 10.4102/sajid.v31i4.76 | |
| Source | Southern African Journal of Infectious Diseases; Vol 31, No 4 (2016); 130-134 2313-1810 2312-0053 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajid.co.za/index.php/sajid/article/view/76/67
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