Molecular detection and characterisation of mumps virus in cerebrospinal fluid in a Gauteng laboratory
Southern African Journal of Infectious Diseases
| Field | Value | |
| Title | Molecular detection and characterisation of mumps virus in cerebrospinal fluid in a Gauteng laboratory | |
| Creator | Brauer, Marieke Wolfaardt, Marianne Webber, Lynne M. Taylor, Maureen B. | |
| Description | The study aimed to determine the presence of mumps virus (MuV) in cerebrospinal fluid (CSF) specimens and to genetically characterise detected MuV strains. A real-time reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the MuV F gene, and characterisation was performed by sequencing of the SH gene. Mumps virus was detected in 1.2% (3/260) of specimens. Phylogenetic analysis of one MuV strain revealed that it clustered with the Jeryl-Lynn and RIT4385 vaccine strains. As far as the authors could ascertain this is the first study to provide viral proof that these vaccine-like strains may be associated with aseptic meningitis. | |
| Publisher | AOSIS Publishing | |
| Date | 2016-03-31 | |
| Identifier | 10.4102/sajid.v31i1.102 | |
| Source | Southern African Journal of Infectious Diseases; Vol 31, No 1 (2016); 29-31 2313-1810 2312-0053 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajid.co.za/index.php/sajid/article/view/102/92
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