In vitro investigation of the toxic effects of extracts of Allium sativum bulbs on adults of Hyalomma marginatum rufipes and Rhipicephalus pulchellus

Journal of the South African Veterinary Association

 
 
Field Value
 
Title In vitro investigation of the toxic effects of extracts of Allium sativum bulbs on adults of Hyalomma marginatum rufipes and Rhipicephalus pulchellus
 
Creator Nchu, F. Magano, S.R. Eloff, J.N.
 
Subject — Allium Sativum; Contact Toxicity Bioassay; Hyalomma Marginatum Rufipes; Rhipicephalus Pulchellus
Description The toxic effects of the extracts of Allium sativum (Garlic) were evaluated against adults of Hyalomma marginatum rufipes and Rhipicephalus pulchellus using three types (Types A, B and C) of contact toxicity bioassays. A. sativum bulbs were extracted with acetone, ethanol and dichloromethane (DCM) solvents. Among these three solvents, it is the DCM extract of A. sativum that appears to have anti-tick activity. In the Type A contact toxicity bioassay, DCM extracts of A. sativum demonstrated a high acaricidal bioactivity against H. m. rufipes with 100 % of ticks killed in less than an hour, and toxicity persisted to the second day. A weak acaricidal activity of aqueous extracts of A. sativum was observed in the Type B contact toxicity bioassay. In the Type C contact toxicity bioassay, a concentration of 24 % w/v of DCM extracts of garlic in sunflower oil (Helianthus annuus) had killed 100% of H. m. rufipes (LC50= 5.9 % w/v) and R. pulchellus (LC50 = 10.3 % w/v) by 24 hours post-treatment of ticks. The results obtained from this study suggest that DCM extract of A. sativum is a potential source of novel acaricidal agents.
 
Publisher AOSIS
 
Contributor —
Date 2005-06-13
 
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format application/pdf
Identifier 10.4102/jsava.v76i2.405
 
Source Journal of the South African Veterinary Association; Vol 76, No 2 (2005); 99-103 2224-9435 1019-9128
 
Language eng
 
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https://jsava.co.za/index.php/jsava/article/view/405/391
 
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Rights Copyright (c) 2005 F. Nchu, S.R. Magano, J.N. Eloff https://creativecommons.org/licenses/by/4.0
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