Phylogenetic analysis to define feline immunodeficiency virus subtypes in 31 domestic cats in South Africa
Journal of the South African Veterinary Association
| Field | Value | |
| Title | Phylogenetic analysis to define feline immunodeficiency virus subtypes in 31 domestic cats in South Africa | |
| Creator | Kann, R. Seddon, J. Kyaw-Tanner, M. Schoeman, J.P. Schoeman, T. Meers, J. | |
| Description | Feline immunodeficiency virus (FIV), a lentivirus, is an important pathogen of domestic cats around the world and has many similarities to human immunodeficiency virus (HIV). A characteristic of these lentiviruses is their extensive genetic diversity, which has been an obstacle in the development of successful vaccines. Of the FIV genes, the envelope gene is the most variable and sequence differences in a portion of this gene have been used to define 5 FIV subtypes (A, B, C, D and E). In this study, the proviral DNA sequence of the V3-V5 region of the envelope gene was determined in blood samples from 31 FIV positive cats from 4 different regions of South Africa. Phylogenetic analysis demonstrated the presence of both subtypes A and C, with subtype A predominating. These findings contribute to the understanding of the genetic diversity of FIV. | |
| Publisher | AOSIS | |
| Date | 2006-06-08 | |
| Identifier | 10.4102/jsava.v77i3.356 | |
| Source | Journal of the South African Veterinary Association; Vol 77, No 3 (2006); 108-113 2224-9435 1019-9128 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://jsava.co.za/index.php/jsava/article/view/356/343
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