In vitro veranderinge in mitochondriale membraan potensiaal, aggresoom formasie en kaspase aktiwiteit deur `n nuwe 17-β-estradiol analoog in bors adenokarsinoomselle
Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie/South African Journal of Science and Technology
| Field | Value | |
| Title | In vitro veranderinge in mitochondriale membraan potensiaal, aggresoom formasie en kaspase aktiwiteit deur `n nuwe 17-β-estradiol analoog in bors adenokarsinoomselle In vitro veranderinge in mitochondriale membraan potensiaal, aggresoom formasie en kaspase aktiwiteit deur `n nuwe 17-β-estradiol analoog in bors adenokarsinoomselle | |
| Creator | Nkandeu, Sandra Mqoco, Thandi V. Visagie, Michelle H. Marais, Sumari Stander, Barend A. Joubert, Annie M. | |
| Description | Die natuurlike metaboliet van estradiol, naamlik 2-metoksieëstradiol (2ME2) oefen antiproliferatiewe en anti-tumor effekte in vitro en in vivo uit met minimale of geen toksisiteit nie. In vitro changes in mitochondrial potential, aggresome formation and caspase activity by a novel 17-beta-estradiol analog in mcf-7 breast adenocarcinoma cells. After a 24 hour exposure time, cells both apoptosis and autophagy were induced. | |
| Publisher | AOSIS | |
| Date | 2012-06-14 | |
| Identifier | 10.4102/satnt.v31i1.297 | |
| Source | Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie; Vol 31, No 1 (2012); 1 bladsy Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie; Vol 31, No 1 (2012); 1 bladsy 2222-4173 0254-3486 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://journals.satnt.aosis.co.za/index.php/satnt/article/view/297/481
https://journals.satnt.aosis.co.za/index.php/satnt/article/view/297/465
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