Antioxidant activity and antimicrobial properties of Entada leptostachya and Prosopis juliflora extracts

Journal of Medicinal Plants for Economic Development

Field Value
Title Antioxidant activity and antimicrobial properties of Entada leptostachya and Prosopis juliflora extracts
Creator Ruto, Mercy C. Ngugi, Christine M. Kareru, Patrick G. Cheruiyot, Kipyegon Rechab, Sylvester O. Madivoli, Edwin S. Mutembei, Jackson K. Kairigo, Pius K. Maina, Ernest G.
Subject CHEMISTRY Antioxidant activity; Total phenolic content; Flavonoid content; DPPH scavenging; β-carotene
Description Background: Natural phytoconstituents produced by plants for their sustenance have been reported to reduce disease.Objectives: This study determined the phytoconstituents, antioxidant and antimicrobial activity of crude methanolic extracts of Entada leptostachya and Prosopis juliflora extracts.Methodology: Antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl and β-carotene assays; the total phenolic and flavonoid were estimated using Folin–Ciocalteau and aluminium chloride, whereas antimicrobial activity was determined using the zone of inhibition method.Results: Screening of the extracts revealed the presence of terpenoids, flavonoids, saponins and phenols. Fourier transform infrared spectra of the extracts revealed presence of hydrogen bonded –OH functional group. E. leptostachya barks had the highest antioxidant activity followed by P. juliflora roots, E. leptostachya roots and P. juliflora leaves [μg/mL]. Prosopis juliflora (roots) had the highest bleaching effect, whereas E. leptostachya (barks) had the lowest bleaching effect. The total flavonoids were determined to be 0.15 ± 0.02 mg/g, 1.18 ± 0.18 mg/g, 0.39 ± 0.05 mg/g and 0.64 ± 0.03 mg/g for E. leptostachya roots, E. leptostachya barks, P. juliflora leaves and P. juliflora roots extracts, respectively. The total phenols were determined to be 0.93 ± 0.18 mg/g, 2.69 ± 0.41 mg/g, 0.62 ± 0.08 mg/g and 0.62 ± 0.08 mg/g for E. leptostachya roots, E. leptostachya barks, P. juliflora roots and P. juliflora leaves extracts. All plant extracts exhibited moderate activity against the growth of selected microorganisms.Conclusion: Antimicrobial and antioxidant activity of the two plants was as a result of secondary metabolites found in the crude extracts.
Publisher AOSIS Publishing
Date 2018-02-27
Type info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion — —
Format text/html application/epub+zip application/xml application/pdf
Identifier 10.4102/jomped.v2i1.31
Source Journal of Medicinal Plants for Economic Development; Vol 2, No 1 (2018); 8 pages 2616-4809 2519-559X
Language eng
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Coverage Kenya — —
Rights Copyright (c) 2018 Mercy C. Ruto, Christine M. Ngugi, Patrick G. Kareru, Kipyegon Cheruiyot, Sylvester O. Rechab, Edwin S. Madivoli, Jackson K. Mutembei, Pius K. Kairigo, Ernest G. Maina