Reserpine for the treatment of refractory mania
South African Journal of Psychiatry
| Field | Value | |
| Title | Reserpine for the treatment of refractory mania | |
| Creator | Eloff, Ingrid Geeske Esterhuysen, Willem | |
| Description | We report a case of refractory mania treated successfully with reserpine. The patient was a 26-year-old man with bipolar I disorder, who had recurrent hospital admissions for manic episodes that failed to respond to multiple mood stabilisers and antipsychotics. The patient also suffered from hypertension. His manic symptoms improved markedly with the addition of reserpine to the treatment regimen. Reserpine is a centrally acting antihypertensive with anti-adrenergic properties. It has been found to reduce the duration of a manic episode rapidly in a small group of studies. This proved to be the case with this patient. Reserpine used in conjunction with other psychotropic medication may be considered in the treatment of refractory mania, but controlled trials are necessary to support our finding more generally. | |
| Publisher | AOSIS | |
| Date | 2014-04-30 | |
| Identifier | 10.4102/sajpsychiatry.v20i1.456 | |
| Source | South African Journal of Psychiatry; Vol 20, No 1 (2014); 2 pages 2078-6786 1608-9685 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajp.org.za/index.php/sajp/article/view/456/457
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