Deficient testosterone levels in men above 45 years with major depressive disorder - an age-matched case control study
South African Journal of Psychiatry
| Field | Value | |
| Title | Deficient testosterone levels in men above 45 years with major depressive disorder - an age-matched case control study | |
| Creator | Dikobe, A M van Staden, C W Reif, S Bornman, M | |
| Description | Background. Symptoms of partial androgen deficiency in ageing men (PADAM) overlap considerably with those of major depressive disorder. The relationship between these conditions is complicated by the usual age-related decline in serum testosterone concentrations.Objectives. To test the hypothesis that depressed men above 45 years of age have lower serum testosterone concentrations than age-matched controls.Method. Serum testosterone fractions of 20 men above the age of 45 years suffering from a major depressive disorder were compared with those of 20 healthy men. An age-matched controlled design was used to account for the usual age-related decline in serum testosterone concentrations.Results. Testosterone concentrations of men suffering from a major depressive disorder were statistically significantly lower than those of an age-matched control group without depression. Conclusion. The role of testosterone deficiency in depressed men needs to be examined further in order for appropriate treatment options to be developed. | |
| Publisher | AOSIS | |
| Date | 2007-08-01 | |
| Identifier | 10.4102/sajpsychiatry.v13i3.21 | |
| Source | South African Journal of Psychiatry; Vol 13, No 3 (2007); 5 2078-6786 1608-9685 | |
| Language | eng | |
| Relation |
The following web links (URLs) may trigger a file download or direct you to an alternative webpage to gain access to a publication file format of the published article:
https://sajp.org.za/index.php/sajp/article/view/21/20
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